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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins / metabolism)
Species Resource Title
Human and Animal Cells NOS-1(RCB1032) PHGDH inhibition and FOXO3 modulation drives PUMA-dependent apoptosis in osteosarcoma.
Mice RBRC02975 Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Human and Animal Cells TE-1(RCB1894) , TE-10(RCB2099) Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.
Human and Animal Cells A172(RCB2530) , T98G(RCB1954) CEP-1347 Targets MDM4 Protein Expression to Activate p53 and Inhibit the Growth of Glioma Cells.
Human and Animal Cells MCF7(RCB1904) Development of fluorizoline analogues as prohibitin ligands that modulate C-RAF signaling, p21 expression and melanogenesis.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells Human BM‐MSCs Human bronchial epithelial cell-derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF-β-WNT crosstalk.
Human and Animal Cells A549 , DU145(RCB2143) , PC-3(RCB2145) , PANC-1(RCB2095) , GI-1(RCB0763) , A431 , MCF7(RCB1904) Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly.
Human and Animal Cells Kato III(RCB2088) , MKN28(RCB1000) , MKN45(RCB1001) Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.
Human and Animal Cells RAW 264(RCB0535) , ST2(RCB0224) Lipopolysaccharide suppresses RANK gene expression in macrophages by down-regulating PU.1 and MITF.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CS-RfA-CG (RDB04390) , pENTR4-H1 (RDB04395) 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
Human and Animal Cells T3M-4(RCB1021) Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.
Human and Animal Cells PC-9(RCB4455) Activation of AXL as a Preclinical Acquired Resistance Mechanism Against Osimertinib Treatment in EGFR-Mutant Non-Small Cell Lung Cancer Cells.
Human and Animal Cells PC-9(RCB4455) ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non-Small Cell Lung Cancer.
Human and Animal Cells HS-Sch-2(RCB2230) , YST-1(RCB2136) , HS-PSS(RCB2362) Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Human and Animal Cells 10T1/2(RCB0247) Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.
Human and Animal Cells TGBC14TKB(RCB1186) , TGBC24TKB(RCB1196) , TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer.
Human and Animal Cells HuH-6(RCB1367) MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma.
Human and Animal Cells 293T(RCB2202) , HHUA(RCB0658) Downregulation of 5-hydroxymethylcytosine is associated with the progression of cervical intraepithelial neoplasia.
Human and Animal Cells NCC-RbC-60(RCB2213) , NCC-RbC-83(RCB2217) , NCC-RbC-54(RCB2208) Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway.