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  • Search Condition : Filter (MeSH = Pyrimidines / pharmacology)
Species Resource Title
Human and Animal Cells HuCCT1(RCB1960) FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma.
Human and Animal Cells RBE(RCB1292) EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma.
Human and Animal Cells RMS-YM(RCB1695) Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcoma cell growth.
Human and Animal Cells Ba/F3(RCB0805) Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.
Human and Animal Cells StromaNKtert(RCB2350) Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia.
Human and Animal Cells Lu-165(RCB1184) SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
Human and Animal Cells A549 , DU145(RCB2143) , PC-3(RCB2145) , PANC-1(RCB2095) , GI-1(RCB0763) , A431 , MCF7(RCB1904) Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly.
Human and Animal Cells HeLa.S3(RCB0191) Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation.
Human and Animal Cells MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
Human and Animal Cells A549 , RERF-LC-AI(RCB0444) , RERF-LC-KJ(RCB1313) Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad.
Human and Animal Cells HuH-6(RCB1367) A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Human and Animal Cells HuCCT1(RCB1960) , RBE(RCB1292) , SSP-25(RCB1293) , HuH-28(RCB1943) TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma.
Human and Animal Cells ST2(RCB0224) Conditioned medium of demineralized freeze-dried bone activates gene expression in periodontal fibroblasts in vitro.
Human and Animal Cells StromaNKtert(RCB2350) BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia.
Human and Animal Cells Ca9-22(RCB1976) , SAS(RCB1974) Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: A possible driving force for tumor progression.
DNA material , Human and Animal Cells Genome Network Project Human cDNA Clone IRAK029O09 (HGX011945) , A549(RCB0098) Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M.
Human and Animal Cells JHOS-2(RCB1521) TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells.
Human and Animal Cells FM3A(RCB0086) β-Estradiol Enhanced Secretion of Lipoprotein Lipase from Mouse Mammary Tumor FM3A Cells.
Human and Animal Cells HeLa(RCB0007) , Hep G2(RCB1648) Adenosine deaminase inhibitor EHNA exhibits a potent anticancer effect against malignant pleural mesothelioma.
Human and Animal Cells HGC-27(RCB0500) , GT3TKB(RCB0885) A novel carbazole topoisomerase II poison, ER-37328: potent tumoricidal activity against human solid tumors in vitro and in vivo.