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  • 23 Hits
  • Search Condition : Filter (MeSH = RNA Splicing / genetics)
Species Resource Title
Human and Animal Cells HeLa(RCB0007) Utility of oligonucleotide in upregulating circular RNA production in a cellular model.
Human and Animal Cells KP4(RCB1005) MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
C.elegans tm872 Cues from mRNA splicing prevent default Argonaute silencing in C. elegans.
Mice RBRCGD000108 , RBRCGD000110 Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
Drosophila pBFv-U6.2 Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
Human and Animal Cells 293T(RCB2202) Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
Drosophila DGRC#201169 SON protects nascent transcripts from unproductive degradation by counteracting DIP1.
Human and Animal Cells 293(RCB1637) , 293T(RCB2202) Forward-genetics analysis of sleep in randomly mutagenized mice.
C.elegans tm3671 , tm290 FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis.
Human and Animal Cells HEV0031 , HEV0032 , HEV0038 , HEV0041 A mutation of COX6A1 causes a recessive axonal or mixed form of Charcot-Marie-Tooth disease.
Human and Animal Cells HGC-27(RCB0500) , NUGC-4(RCB1939) , Lu99(RCB1900) , T3M-11(RCB1022) , MDA-MB-453(RCB1192) High antitumor activity of pladienolide B and its derivative in gastric cancer.
Silkworms Suzu19-1 Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori.
Human and Animal Cells HuH-7 , Hep G2 Polyunsaturated Branched-Chain Fatty Acid Geranylgeranoic Acid Induces Unfolded Protein Response in Human Hepatoma Cells.
Zebrafish Ddx46 is required for multi-lineage differentiation of hematopoietic stem cells in zebrafish.
Drosophila 11274R-1 , 11274R-3 Multifunctional RNA processing protein SRm160 induces apoptosis and regulates eye and genital development in Drosophila.
C.elegans tm2625 , tm2607 RSR-2, the Caenorhabditis elegans ortholog of human spliceosomal component SRm300/SRRM2, regulates development by influencing the transcriptional machinery.
Silkworms A role for transcription from a piRNA cluster in de novo piRNA production.
Human and Animal Cells COS-1(RCB0143) X-linked adrenal hypoplasia congenita caused by a novel intronic mutation of the DAX-1 gene.
Mice RBRC01680 SMOC1 is essential for ocular and limb development in humans and mice.
Human and Animal Cells HCE-T(RCB1384) Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells.