• 21 Hits
  • 検索条件 : 絞込み (MeSH = Recombinant Fusion Proteins / pharmacology)
生物種 リソース名 タイトル
ヒト・動物細胞 SHP1^(-) DT40(RCB1466) , SHP1^(-)/SHP2^(-) DT40(RCB1501) , SHP2^(-) DT40(RCB1502) , SHIP^(-) DT40(RCB1465) Src homology 2 domain-containing protein-tyrosine phosphatases, SHP-1 and SHP-2, are required for platelet endothelial cell adhesion molecule-1/CD31-mediated inhibitory signaling.
ヒト・動物細胞 10T1/2(RCB0247) Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin.
ヒト・動物細胞 BALB/3T3 clone A31(RCB0005) Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors.
ヒト・動物細胞 MG-63(RCB1890) Inhibition of vitronectin-mediated haptotaxis and haptoinvasion of MG-63 cells by domain 5 (D5(H)) of human high-molecular-weight kininogen and identification of a minimal amino acid sequence.
ヒト・動物細胞 ST2(RCB0224) Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells.
遺伝子材料 pGEX-6P-3/GST-TAT-ODD/3-0-Casp3 (RDB14403) , pEF/HRE-Fluc (RDB14404). Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model.
ヒト・動物細胞 10T1/2(RCB0247) Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer.
ヒト・動物細胞 The SH2 domain-containing inositol 5-phosphatase SHIP1 is recruited to the intracytoplasmic domain of human FcgammaRIIB and is mandatory for negative regulation of B cell activation.
ヒト・動物細胞 Generation of a humanized monoclonal antibody against human parathyroid hormone-related protein and its efficacy against humoral hypercalcemia of malignancy.
ヒト・動物細胞 MC3T3-E1(RCB1126) , C2C12(RCB0987) Continuous inhibition of MAPK signaling promotes the early osteoblastic differentiation and mineralization of the extracellular matrix.
ヒト・動物細胞 ST2(RCB0224) Characterization of structural domains of human osteoclastogenesis inhibitory factor.
ヒト・動物細胞 293T(RCB2202) Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.
ヒト・動物細胞 253G1(HPS0002) , 201B7(HPS0063) Elimination of tumorigenic human pluripotent stem cells by a recombinant lectin-toxin fusion protein.
細胞性粘菌 S00486 A putative receptor mediating cell-density sensing in Dictyostelium.
遺伝子材料 pGa981-6 (RDB06776) Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region.
ヒト・動物細胞 MKN45(RCB1001) , MKN28(RCB1000) Potent inhibition of human gastric cancer by HER2-directed induction of apoptosis with anti-HER2 antibody and caspase-3 fusion protein.
ヒト・動物細胞 Saos-2(RCB0428) Efficient growth inhibition of human osteosarcoma cells using a peptide derived from the MDM-2-binding site of p53.
ヒト・動物細胞 F-36E(RCB0776) Natural form of noncytolytic flexible human Fc as a long-acting carrier of agonistic ligand, erythropoietin.
ヒト・動物細胞 F-36E(RCB0776) The prolonged half-lives of new erythropoietin derivatives via peptide addition.
遺伝子材料 Mouse E-cadherin full length cDNA (RDB01184) Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells.