Ito R, Kanno H, Takahashi A, Matsumoto R, Kobayashi N, Yoshida T, Saito T.
Title
Efficient growth inhibition of human osteosarcoma cells using a peptide derived from the MDM-2-binding site of p53.
Journal
Protein Pept Lett
Abstract
Protein transduction therapy is a promising alternative to gene therapy, but has not previously been investigated for osteosarcoma. We here demonstrate efficient growth inhibition of human osteosarcoma cells using a p53 peptide. Our result suggests that protein transduction therapy has significant potential as a novel therapeutic approach for osteosarcoma.
