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  • 検索条件 : 絞込み (MeSH = Sirolimus / pharmacology)
生物種 リソース名 タイトル
細胞性粘菌 G90426 mTORC1 pathway activity biases cell fate choice.
ヒト・動物細胞 ATDC5(RCB0565) Investigation of the effectiveness of intermittent electromagnetic field stimulation for early internal cartilaginous ossification in prechondrocytic ATDC5 cells.
ヒト・動物細胞 293T(RCB2202) Engineering of Extracellular Vesicles for Small Molecule-Regulated Cargo Loading and Cytoplasmic Delivery of Bioactive Proteins.
実験動物マウス RBRC00806 TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model.
ヒト・動物細胞 HiPS-RIKEN-2F(HPS0014) Efficient protocol for the differentiation of kidney podocytes from induced pluripotent stem cells, involving the inhibition of mTOR.
ヒト・動物細胞 Hep G2 Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma.
実験動物マウス RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
ヒト・動物細胞 HS-Sch-2(RCB2230) , HS-PSS(RCB2362) , YST-1(RCB2136) Prognostic significance of AKT/mTOR and MAPK pathways and antitumor effect of mTOR inhibitor in NF1-related and sporadic malignant peripheral nerve sheath tumors.
ショウジョウバエ DGRC#104863 A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.
ヒト・動物細胞 HuH-7(RCB1366) Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
ヒト・動物細胞 HuH-7 mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
ヒト・動物細胞 RAW 264(RCB0535) , THP-1(RCB1189) GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.
ヒト・動物細胞 409B2(HPS0076) Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.
ゼブラフィッシュ Tg(isl1:GFP)rw0 Exosc2 deficiency leads to developmental disorders by causing a nucleotide pool imbalance in zebrafish.
実験動物マウス RBRC02231 RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
ヒト・動物細胞 TE-8(RCB2098) , TE-9(RCB1988) , TE-15(RCB1951) Chemokine (C-C Motif) Ligand 1 Derived from Tumor-Associated Macrophages Contributes to Esophageal Squamous Cell Carcinoma Progression via CCR8-Mediated Akt/Proline-Rich Akt Substrate of 40 kDa/Mammalian Target of Rapamycin Pathway.
ヒト・動物細胞 C2C12(RCB0987) Dietary protein decreases exercise endurance through rapamycin-sensitive suppression of muscle mitochondria.
ヒト・動物細胞 GCIY(RCB0555) ERas enhances resistance to CPT-11 in gastric cancer.
線虫 tm1340 Food-Dependent Plasticity in Caenorhabditis elegans Stress-Induced Sleep Is Mediated by TOR-FOXA and TGF-β Signaling.
線虫 tm776 , tm1146 The genetics of isoflurane-induced developmental neurotoxicity.