• 75 Hits
  • 検索条件 : 絞込み (MeSH = TOR Serine-Threonine Kinases / metabolism)
生物種 リソース名 タイトル
実験動物マウス RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
ヒト・動物細胞 HuH-7(RCB1366) Ferroptosis-related gene glutathione peroxidase 4 promotes reprogramming of glucose metabolism via Akt-mTOR axis in intrahepatic cholangiocarcinoma.
ヒト・動物細胞 HOS(RCB0992) , 293T(RCB2202) , Saos-2(RCB3688) , A549(RCB0098) PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
ヒト・動物細胞 CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
ヒト・動物細胞 MG6(RCB2403) 3',4'-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT-mTOR and NF-κB Pathways.
線虫 A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk.
ヒト・動物細胞 MG-63(RCB1890) , 143B/TK^(-)neo^(R)(RCB0701) Compound Library Screening for Synergistic Drug Combinations: mTOR Inhibitor and Proteasome Inhibitor Effective Against Osteosarcoma Cells.
ヒト・動物細胞 HK2(RCB0720) Enhanced inflammatory damage by microRNA-136 targeting Klotho expression in HK-2 cells by modulating JAK/STAT pathway.
一般微生物 JCM2009 Surface-layer protein produced by Lactobacillus crispatus JCM 2009 ameliorates lipopolysaccharide-induced inflammation through autophagy cross-talk with the NF-κB signaling pathway.
ゼブラフィッシュ Tg(UAS:EGFP) ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
ヒト・動物細胞 MC3T3-E1(RCB1126) Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis.
ヒト・動物細胞 PANC-1(RCB2095) Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate.
ヒト・動物細胞 HuH-7(RCB1366) Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
ヒト・動物細胞 RAW 264(RCB0535) , THP-1(RCB1189) GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.
ヒト・動物細胞 PANC-1(RCB2095) GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway.
ヒト・動物細胞 HuH-7(RCB1366) Targeting cap-dependent translation to inhibit Chikungunya virus replication: selectivity of p38 MAPK inhibitors to virus-infected cells due to autophagy-mediated down regulation of phospho-ERK.
ヒト・動物細胞 HuCCT1(RCB1960) , SSP-25(RCB1293) , RBE(RCB1292) , YSCCC(RCB1549) , TGBC24TKB(RCB1196) , TFK-1(RCB2537) Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity.
ヒト・動物細胞 409B2(HPS0076) Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.
ヒト・動物細胞 KP4(RCB1005) , PK-1(RCB1972) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
ヒト・動物細胞 HGC-27(RCB0500) CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection.