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  • Search Condition : Filter (MeSH = TOR Serine-Threonine Kinases / metabolism)
Species Resource Title
Human and Animal Cells OS-RC-2(RCB0735) Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression.
Human and Animal Cells HiPS-RIKEN-2F(HPS0014) Efficient protocol for the differentiation of kidney podocytes from induced pluripotent stem cells, involving the inhibition of mTOR.
Algae NIES-3377 Development of a rapamycin-inducible protein-knockdown system in the unicellular red alga Cyanidioschyzon merolae.
Mice RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
Human and Animal Cells HuH-7(RCB1366) Ferroptosis-related gene glutathione peroxidase 4 promotes reprogramming of glucose metabolism via Akt-mTOR axis in intrahepatic cholangiocarcinoma.
Human and Animal Cells HOS(RCB0992) , 293T(RCB2202) , Saos-2(RCB3688) , A549(RCB0098) PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
Human and Animal Cells CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
Human and Animal Cells MG6(RCB2403) 3',4'-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT-mTOR and NF-κB Pathways.
C.elegans tm1027 , tm1192 , tm504 , tm1964 , tm6454 , tm6502 , tm11887 , tm4948 A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk.
Human and Animal Cells MG-63(RCB1890) , 143B/TK^(-)neo^(R)(RCB0701) Compound Library Screening for Synergistic Drug Combinations: mTOR Inhibitor and Proteasome Inhibitor Effective Against Osteosarcoma Cells.
Human and Animal Cells HK2(RCB0720) Enhanced inflammatory damage by microRNA-136 targeting Klotho expression in HK-2 cells by modulating JAK/STAT pathway.
General Microbes JCM2009 Surface-layer protein produced by Lactobacillus crispatus JCM 2009 ameliorates lipopolysaccharide-induced inflammation through autophagy cross-talk with the NF-κB signaling pathway.
Zebrafish Tg(UAS:EGFP) ubtor Mutation Causes Motor Hyperactivity by Activating mTOR Signaling in Zebrafish.
Human and Animal Cells MC3T3-E1(RCB1126) Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis.
Human and Animal Cells PANC-1(RCB2095) Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate.
Human and Animal Cells HuH-7(RCB1366) Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
Human and Animal Cells RAW 264(RCB0535) , THP-1(RCB1189) GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy.
Human and Animal Cells PANC-1(RCB2095) GDP Induces PANC-1 Human Pancreatic Cancer Cell Death Preferentially under Nutrient Starvation by Inhibiting PI3K/Akt/mTOR/Autophagy Signaling Pathway.
Human and Animal Cells HuH-7(RCB1366) Targeting cap-dependent translation to inhibit Chikungunya virus replication: selectivity of p38 MAPK inhibitors to virus-infected cells due to autophagy-mediated down regulation of phospho-ERK.
Human and Animal Cells HuCCT1(RCB1960) , SSP-25(RCB1293) , RBE(RCB1292) , YSCCC(RCB1549) , TGBC24TKB(RCB1196) , TFK-1(RCB2537) Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity.