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  • 検索条件 : 絞込み (MeSH = TOR Serine-Threonine Kinases / metabolism)
生物種 リソース名 タイトル
一般微生物 JCM10645 Solobacterium moorei promotes tumor progression via the Integrin α2/β1-PI3K-AKT-mTOR-C-myc signaling pathway in colorectal cancer.
実験動物マウス RBRC05737 Barcoded viral tracing of single-cell interactions in central nervous system inflammation.
ショウジョウバエ The cell autonomous and non-autonomous functions of Rab27 in longevity and neuroprotection in Drosophila.
ゼブラフィッシュ UAS:GFP Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signaling.
ヒト・動物細胞 PANC-1(RCB2095) Anti-cancer activity of 7-methoxyheptaphylline from Clausena harmandiana against PANC-1 pancreatic cancer cells and its sustainable extraction method.
ヒト・動物細胞 Ba/F3(RCB4476) The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling.
ショウジョウバエ Supplementation of essential amino acids suppresses age-associated sleep loss and sleep fragmentation but not loss of rhythm strength under yeast-restricted malnutrition in Drosophila.
実験動物マウス RBRC00806 Rapamycin improves satellite cells' autophagy and muscle regeneration during hypercapnia.
遺伝子材料 pCMV5-Flag-Sin1 (RDB20790) , pMAL-c2X-Sin1 (RDB20791) FilGAP regulates tumor growth in Glioma through the regulation of mTORC1 and mTORC2.
ヒト・動物細胞 , 遺伝子材料 OS-RC-2(RCB0735) , CSII-EF-MCS-IRES2-Venus (RDB04384) , pCSII-CLDN2 (RDB21015) , pCSII-CLDN7 (RDB21020) , pCSII-CLDN8 (RDB21021) , pCSII-CLDN10B (RDB21024) , pCSII-CLDN11 (RDB21025) , pCSII-CLDN16 (RDB21028) , pCSII-LAT1-HA (RDB21029) , pCSII-LAT1-mTM4-HA (RDB21030) Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression.
ヒト・動物細胞 HiPS-RIKEN-2F(HPS0014) Efficient protocol for the differentiation of kidney podocytes from induced pluripotent stem cells, involving the inhibition of mTOR.
ヒト・動物細胞 JHOS-2(RCB1521) A multiplex single-cell RNA-Seq pharmacotranscriptomics pipeline for drug discovery.
藻類 NIES-3377 Development of a rapamycin-inducible protein-knockdown system in the unicellular red alga Cyanidioschyzon merolae.
実験動物マウス RBRC01872 Membrane protein CNNM4-dependent Mg2+ efflux suppresses tumor progression.
ヒト・動物細胞 HuH-7(RCB1366) Ferroptosis-related gene glutathione peroxidase 4 promotes reprogramming of glucose metabolism via Akt-mTOR axis in intrahepatic cholangiocarcinoma.
ヒト・動物細胞 HOS(RCB0992) , 293T(RCB2202) , Saos-2(RCB3688) , A549(RCB0098) PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
ヒト・動物細胞 CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
ヒト・動物細胞 MG6(RCB2403) 3',4'-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT-mTOR and NF-κB Pathways.
線虫 tm1027 , tm1192 , tm504 , tm1964 , tm6454 , tm6502 , tm11887 , tm4948 A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk.
ヒト・動物細胞 MG-63(RCB1890) , 143B/TK^(-)neo^(R)(RCB0701) Compound Library Screening for Synergistic Drug Combinations: mTOR Inhibitor and Proteasome Inhibitor Effective Against Osteosarcoma Cells.