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Species Resource Title
Zebrafish flightless mi372 Biallelic variants in FLII cause pediatric cardiomyopathy by disrupting cardiomyocyte cell adhesion and myofibril organization.
Human and Animal Cells SCCKN(RCB0441) , SCCTF(RCB0442) , T3M-1 , HSQ-89(RCB0789) Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers.
Human and Animal Cells V79(RCB0008) DNA-double strand breaks enhance the expression of major histocompatibility complex class II through the ATM-NF-κΒ-IRF1-CIITA pathway.
Human and Animal Cells Li-7(RCB1941) Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma.
Human and Animal Cells Lu-134-A(RCB0466) , Lu-134-B(RCB0467) , Lu-139(RCB0469) YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.
Human and Animal Cells HuCCT1(RCB1960) Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes.
DNA material pKM2L-phIL1B (RDB05526) TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation.
DNA material , Human and Animal Cells pAxCAwt (RDB01678) , ST2(RCB0224) , 10T1/2(RCB0247) Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.
Human and Animal Cells H-EMC-SS(RCB0508) , ATDC5(RCB0565) Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9.
Human and Animal Cells ST2(RCB0224) Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes.
General Microbes JCM 16667 Lineage-specific SoxR-mediated Regulation of an Endoribonuclease Protects Non-enteric Bacteria from Redox-active Compounds.
Human and Animal Cells KG-1(RCB1166) , 293(RCB1637) Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23).
Human and Animal Cells IEC 6(RCB0993) Heparin-binding EGF-like growth factor gene transcription regulated by Cdx2 in the intestinal epithelium.
Human and Animal Cells COS-7(RCB0539) The polymorphism in the caudal-related homeodomain protein Cdx-2 binding element in the human vitamin D receptor gene.
Human and Animal Cells COS-7(RCB0539) , Hep G2(RCB0459) The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine.
Human and Animal Cells HeLa S3 (SC)(RCB0271) Identification of multiple regulatory elements of human L-histidine decarboxylase gene.
Human and Animal Cells Hep G2(RCB1648) , HuH-7(RCB1942) miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
DNA material pSCI (mu , alpha) (RDB02861) The AID enzyme induces class switch recombination in fibroblasts.
DNA material 8xGT-IIC-LucII (RDB08067) , pcDNA3.1-pA83-HA-Yap (RDB12190) , pcDNA3.1-pA83-Lats2 (RDB12200) YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function.