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  • Search Condition : Filter (MeSH = Tumor Suppressor Protein p53 / genetics)
Species Resource
DNA material AxCALacZ (RDB1745) Effect of an adenoviral vector that expresses the canine p53 gene on cell growth of canine osteosarcoma and mammary adenocarcinoma cell lines.
Mice p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation.
Mice A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.
Mice C3H/HeN-TgH(p53) Activation of interferon-stimulated genes by gamma-ray irradiation independently of the ataxia telangiectasia mutated-p53 pathway.
Medaka HdrR-II1 (IB178) , Kyoto-Cab (OK-Cab(MT830)) , TILLING_MUTANT High-resolution melting curve analysis for rapid detection of mutations in a Medaka TILLING library.
C.elegans tm536 , tm586 C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage.
Medaka HdrR-II1 (IB178) , Hd-rR-p53(y186x) (MT1166) , p53(y186x) (MT893) Gamma-ray irradiation promotes premature meiosis of spontaneously differentiating testis-ova in the testis of p53-deficient medaka (Oryzias latipes).
DNA material AxCAUT (RDB02050) , pAxcwit (RDB03120) Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models.
Mice C57BL-p53+/-(RBRC01361) Etoposide induces TRP53-dependent apoptosis and TRP53-independent cell cycle arrest in trophoblasts of the developing mouse placenta.
Mice C57BL-p53+/-(RBRC01361) Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts.
Mice B6;129-Atg5<tm1Nmz>(RBRC02231) Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
DNA material pNF-kappaB RE-TK hRluc(F) (RDB05576) , pGL4-phTP53 (RDB07330) , pCMFlag_hsTP53 (RDB06754) , pCMV_S-FLAG (RDB05956). NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells.
DNA material pMXs-SB11-IRES-puro (RDB16060) , pT2/CMV-PDGFA-IRES-DsRed (RDB16061) , pT2/shp53/shNf1/SV40-GFP (RDB16062) , pT2/shp53/shNf1/CMV-PDGFA-IRES-DsRed (RDB16063) Spontaneous development of intratumoral heterogeneity in a transposon-induced mouse model of glioma.
C.elegans tm2427 , tm853 Stress-Induced Sleep After Exposure to Ultraviolet Light Is Promoted by p53 in Caenorhabditis elegans.
C.elegans tm2176 ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline.
DNA material CSII-CMV-RfA (RDB04386) , CSII-EF-RfA (RDB04387). A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression.
Medaka p53(E241x) MT894 Early life exposure to a rodent carcinogen propiconazole fungicide induces oxidative stress and hepatocarcinogenesis in medaka fish.
Mice B6.Cg-Trp53<tm1Sia>/Rbrc(RBRC01361) Development of a functional thyroid model based on an organoid culture system.
DNA material CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.