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  • Search Condition : Filter (MeSH = Tumor Suppressor Protein p53 / metabolism)
Species Resource Title
C.elegans tm5218 , tm5124 , tm51240 Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53.
Human and Animal Cells ST2(RCB224) , HS-Os-1(RCB2229) C/ebpα represses the oncogenic Runx3-Myc axis in p53-deficient osteosarcoma development.
Human and Animal Cells PANC-1(RCB2095) Reduction of HIF-1α/PD-L1 by Catalytic Topoisomerase Inhibitor Induces Cell Death Through Caspase Activation in Cancer Cells Under Hypoxia.
Human and Animal Cells CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
Mice RBRC03556 Inherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein.
Human and Animal Cells 293T(RCB2202) Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma.
Human and Animal Cells NALM-6(RCB1933) TESTIN Induces Rapid Death and Suppresses Proliferation in Childhood B Acute Lymphoblastic Leukaemia Cells.
C.elegans tm1473 , tm1145 , tm1125 Caenorhabditis elegans NHR-14/HNF4α regulates DNA damage-induced apoptosis through cooperating with cep-1/p53.
C.elegans tm1298 , tm1145 , tm1937 , tm1524 , tm2842 DNA topoisomerase 3 is required for efficient germ cell quality control.
Human and Animal Cells 293(RCB1637) , CACO-2(RCB0988) , LoVo(RCB1639) Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels.
Human and Animal Cells HiPS-RIKEN-2A(HPS0009) ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response : ΔNp63α may cause genomic instability in epithelial stem cells.
Human and Animal Cells MKN45(RCB1001) , TE-6(RCB1950) , RBE(RCB1292) GET4 is a novel driver gene in colorectal cancer that regulates the localization of BAG6, a nucleocytoplasmic shuttling protein.
Human and Animal Cells A549(RCB0098) A Methoxyflavanone from Perilla frutescens Induces Cellular Senescence in A549 Human Lung Adenocarcinoma Cells but Not in Normal Human Bronchial Epithelial Cells.
DNA material , Human and Animal Cells pENTR4-H1tetOx1 (RDB07916) , CS-RfA-ETBsd (RDB07917) , CS-RfA-ETV (RDB08020) , CS-RfA-ETR (RDB08362) , 293T(RCB2202) Chlorambucil-conjugated PI-polyamides (Chb-M'), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation.
Human and Animal Cells A172(RCB2530) , T98G(RCB1954) CEP-1347 Targets MDM4 Protein Expression to Activate p53 and Inhibit the Growth of Glioma Cells.
Human and Animal Cells HeLa Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents.
Human and Animal Cells KGN(RCB1154) FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.
Human and Animal Cells HEp-2(RCB1889) CCL299, a Benzimidazole Derivative Induces G1 Phase Arrest and Apoptosis in Cancer Cells.
Zebrafish , Human and Animal Cells Tg(6xTcf/LefBS-miniP:d2EGFP) , Cle-H3(RCB0549) A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.
Human and Animal Cells TE-1(RCB1894) , TE-4(RCB2097) , TE-5(RCB1949) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutation.