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  • Search Condition : Filter (MeSH = Up-Regulation*)
Species Resource Title
Arabidopsis / Cultured plant cells, genes pda05670 , pda00509 Overexpression of the calcineurin target CRZ1 provides freeze tolerance and enhances the fermentative capacity of baker's yeast.
Human and Animal Cells MH7A(RCB1512) Helicobacter pylori upregulates PAD4 expression via stabilising HIF-1α to exacerbate rheumatoid arthritis.
Human and Animal Cells KGN(RCB1154) Hsa_circ_0043532 contributes to PCOS through upregulation of CYP19A1 by acting as a ceRNA for hsa-miR-1270.
Human and Animal Cells HuH7 TERT upregulation promotes cell proliferation via degradation of p21 and increases carcinogenic potential.
Human and Animal Cells NOS-1(RCB1032) Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma.
Human and Animal Cells Ca9-22(RCB1976) Oncogenic E6 and/or E7 proteins drive proliferation and invasion of human papilloma virus‑positive head and neck squamous cell cancer through upregulation of Ror2 expression.
Human and Animal Cells MKN45(RCB1001) , TE-6(RCB1950) , RBE(RCB1292) GET4 is a novel driver gene in colorectal cancer that regulates the localization of BAG6, a nucleocytoplasmic shuttling protein.
Human and Animal Cells 293T(RCB2202) Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression.
Human and Animal Cells OS-RC-2(RCB0735) Heterogenous expression of endoglin marks advanced renal cancer with distinct tumor microenvironment fitness.
Arabidopsis / Cultured plant cells, genes rpc00003 Vanillylacetone up-regulates anthocyanin accumulation and expression of anthocyanin biosynthetic genes by inducing endogenous abscisic acid in grapevine tissues.
Human and Animal Cells CACO-2(RCB0988) Mitotic checkpoint regulator RAE1 promotes tumor growth in colorectal cancer.
Human and Animal Cells HCT116(RCB2979) NADPH oxidase 5 has a crucial role in cellular motility of colon cancer cells.
Human and Animal Cells MCF7(RCB1904) Gemcitabine treatment enhances HER2 expression in low HER2-expressing breast cancer cells and enhances the antitumor effects of trastuzumab emtansine.
Human and Animal Cells HuH-7(RCB1366) Cancer‑associated fibroblast‑induced M2‑polarized macrophages promote hepatocellular carcinoma progression via the plasminogen activator inhibitor‑1 pathway.
Human and Animal Cells U-937 DE-4(RCB0435) Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages.
Human and Animal Cells CTB-1(RCB1316) Overexpression of B-cell lymphoma 6 alters gene expression profile in a myeloma cell line and is associated with decreased DNA damage response.
Human and Animal Cells ST2(RCB0224) , MC3T3-E1(RCB1126) The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells.
Human and Animal Cells NIH/3T3(RCB2767) Hyperoxia causes diffuse alveolar damage through mechanisms involving upregulation of c-Myc/Bax and enhanced production of reactive oxygen species.
Human and Animal Cells HHUA(RCB0658) Dual-specificity phosphatase 6 plays a critical role in the maintenance of a cancer stem-like cell phenotype in human endometrial cancer.
Human and Animal Cells ATDC5(RCB0565) Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis.