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  • Search Condition : Filter (MeSH = beta-Globins / genetics)
Species Resource Title
Human and Animal Cells HUDEP-2(RCB4557) Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
Human and Animal Cells HUDEP-2(RCB4557) Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease.
Human and Animal Cells HUDEP-2(RCB4557) Molecular epidemiology and hematologic characterization of δβ-thalassemia and hereditary persistence of fetal hemoglobin in 125,661 families of greater Guangzhou area, the metropolis of southern China.
Human and Animal Cells HUDEP-2(RCB4557) A unified model of human hemoglobin switching through single-cell genome editing.
Human and Animal Cells HUDEP-2(RCB4557) Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells.
Human and Animal Cells HUDEP-2(RCB4557) In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice.
Human and Animal Cells HUDEP-2(RCB4557) Engineering of the endogenous HBD promoter increases HbA2.
Human and Animal Cells HUDEP-2(RCB4557) A novel gain-of-function PIP4K2A mutation elevates the expression of β-globin and aggravates the severity of α-thalassemia.
Human and Animal Cells HUDEP-2(RCB4557) Prime Editor 3 Mediated Beta-Thalassemia Mutations of the HBB Gene in Human Erythroid Progenitor Cells.
Human and Animal Cells HUDEP-2(RCB4557) Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Human and Animal Cells HUDEP-2(RCB4557) Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells.
Human and Animal Cells HUDEP-1(RCB4556) , HUDEP-2(RCB4557) Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Human and Animal Cells HUDEP-2(RCB4557) DNA·RNA triple helix formation can function as a cis-acting regulatory mechanism at the human β-globin locus.
Chicken / Quail Molecular cloning of chicken TET family genes and role of chicken TET1 in erythropoiesis.
Medaka d-rR , AD-1/GFP (TG126) 1kbp 5' upstream sequence enables developmental stage-specific expressions of globin genes in the fish, medaka Oryzias latipes.