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  • Search Condition : Filter (MeSH = eIF-2 Kinase / genetics)
Species Resource Title
C.elegans , Human and Animal Cells tm4397 , tm1340 , tm1944 , 293T(RCB2202) ER proteostasis regulators cell-non-autonomously control sleep.
Drosophila DGRC#142049 , DGRC#105823 The transcription factor Xrp1 is required for PERK-mediated antioxidant gene induction in Drosophila.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.
C.elegans tm794 RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of beta-integrin.
C.elegans tm1153 , tm849 , tm5409 RNA surveillance is required for endoplasmic reticulum homeostasis.
C.elegans tm4525 Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2.
Human and Animal Cells RAW 264(RCB0535) Activating transcription factor 4 links metabolic stress to interleukin-6 expression in macrophages.
Human and Animal Cells Sa3(RCB0980) Interaction between PKR and PACT mediated by LPS-inducible NF-κB in human gingival cells.
Human and Animal Cells HeLa(RCB0007) Double-stranded RNA-activated protein kinase inhibits hepatitis C virus replication but may be not essential in interferon treatment.
Drosophila 4353R-2 The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model.
Yeast FY10303 , FY9930 Cellular stress induces cytoplasmic RNA granules in fission yeast.