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  • 検索条件 : 絞込み (MeSH = ras Proteins / genetics)
生物種 リソース名 タイトル
線虫 tm810 Discovery of nonautonomous modulators of activated Ras.
ショウジョウバエ EGFRAP encodes a new negative regulator of the EGFR acting in both normal and oncogenic EGFR/Ras-driven tissue morphogenesis.
ヒト・動物細胞 CW-2(RCB0778) Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling.
ヒト・動物細胞 HeLa(RCB0007) Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling.
ヒト・動物細胞 MMAc·SF(RCB1200) Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.
ヒト・動物細胞 COLO205(RCB2127) , JHCOLOYI(RCB1706) , PMF-ko14(RCB1426) EGFR Downregulation after Anti-EGFR Therapy Predicts the Antitumor Effect in Colorectal Cancer.
ヒト・動物細胞 HKBML(RCB0820) Metabolome Analysis Reveals Excessive Glycolysis via PI3K/AKT/mTOR and RAS/MAPK Signaling in Methotrexate-Resistant Primary CNS Lymphoma-Derived Cells.
ショウジョウバエ 8486R-3 , 7563R-3 Dissemination of RasV12-transformed cells requires the mechanosensitive channel Piezo.
線虫 tm2760 , tm5205 , tm2255 , tm6137 Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.
ヒト・動物細胞 Ba/F3(RCB0805) RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia.
ショウジョウバエ Ras2, the TC21/R-Ras2 Drosophila homologue, contributes to insulin signalling but is not required for organism viability.
ヒト・動物細胞 HuH-7 HIF-1α-induced RIT1 promotes liver cancer growth and metastasis and its deficiency increases sensitivity to sorafenib.
細胞性粘菌 Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells.
線虫 tm748 Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory.
ヒト・動物細胞 Ca9-22(RCB1976) The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
ヒト・動物細胞 Hep G2(RCB1886) δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling.
遺伝子材料 CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.
線虫 tm853 Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling.
線虫 tm3425 , tm2508 Autophagy modulates miRNA-mediated gene silencing and selectively degrades AIN-1/GW182 in C. elegans.
ヒト・動物細胞 EBC-1(RCB1965) Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells.