Reference - Detail
| RRC ID | 17449 |
|---|---|
| Author | Ugwu CU, Tokiwa Y, Ichiba T. |
| Title | Production of (R)-3-hydroxybutyric acid by fermentation and bioconversion processes with Azohydromonas lata. |
| Journal | Bioresour Technol |
| Abstract |
Feasibility of producing (R)-3-hydroxybutyric acid ((R)-3-HB) using wild type Azohydromonas lata and its mutants (derived by UV mutation) was investigated. A. lata mutant (M5) produced 780 m g/l in the culture broth when sucrose was used as the carbon source. M5 was further studied in terms of its specificity with various bioconversion substrates for production of (R)-3-HB. (R)-3-HB concentration produced in the culture broth by M5 mutant was 2.7-fold higher than that of the wild type strain when sucrose (3% w/v) and (R,S)-1,3-butanediol (3% v/v) were used as carbon source and bioconversion substrate, respectively. Bioconversion of resting cells (M5) with glucose (1% v/w), ethylacetoacetate (2% v/v), and (R,S)-1,3-butanediol (3% v/v), resulted in (R)-3-HB concentrations of 6.5 g/l, 7.3g/l and 8.7 g/l, respectively. |
| Volume | 102(12) |
| Pages | 6766-8 |
| Published | 2011-6-1 |
| DOI | 10.1016/j.biortech.2011.03.073 |
| PII | S0960-8524(11)00430-5 |
| PMID | 21507620 |
| MeSH | 3-Hydroxybutyric Acid / biosynthesis* Alcaligenaceae / genetics Alcaligenaceae / metabolism* Biotechnology / methods* Butylene Glycols Culture Media Fermentation Mutagenesis / radiation effects Mutation / genetics Species Specificity Sucrose Ultraviolet Rays |
| IF | 7.539 |
| Times Cited | 11 |
| WOS Category | BIOTECHNOLOGY & APPLIED MICROBIOLOGY AGRICULTURAL ENGINEERING ENERGY & FUELS |
| Altmetric score |
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 5 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM 20724 |