論文 - 詳細
| RRC ID | 3138 |
|---|---|
| 著者 | Araki A, Tsuda M, Kubota T, Mikami Y, Fromont J, Kobayashi J. |
| タイトル | Nagelamide J, a novel dimeric bromopyrrole alkaloid from a sponge Agelas species. |
| ジャーナル | Org Lett |
| Abstract |
A novel dimeric bromopyrrole alkaloid, nagelamide J (1), with antimicrobial activity has been isolated from an Okinawan marine sponge Agelas species, and the structure and stereochemistry were elucidated from spectroscopic data. Nagelamide J (1) is the first bromopyrrole alkaloid possessing a cyclopentane ring fused to an amino imidazole ring. |
| 巻・号 | 9(12) |
| ページ | 2369-71 |
| 公開日 | 2007-6-7 |
| DOI | 10.1021/ol0707867 |
| PMID | 17503838 |
| MeSH | Agelas / chemistry* Alkaloids / chemistry* Alkaloids / isolation & purification Alkaloids / pharmacology Animals Cryptococcus neoformans / drug effects Magnetic Resonance Spectroscopy / methods Microbial Sensitivity Tests Models, Molecular Molecular Structure Pyrroles / chemistry* Pyrroles / isolation & purification Pyrroles / pharmacology Sensitivity and Specificity Species Specificity Staphylococcus aureus / drug effects Structure-Activity Relationship |
| IF | 6.091 |
| 引用数 | 36 |
| WOS 分野 | CHEMISTRY, ORGANIC |
| リソース情報 | |
| 病原微生物 | NA |