| RRC ID |
3575
|
| Author |
Gorjánácz M, Jaedicke A, Mattaj IW.
|
| Title |
What can Caenorhabditis elegans tell us about the nuclear envelope?
|
| Journal |
FEBS Lett
|
| Abstract |
The nuclear envelope (NE) of the eukaryotic cell provides an essential barrier that separates the nuclear compartment from the cytoplasm. In addition, the NE is involved in essential functions such as nuclear stability, regulation of gene expression, centrosome separation and nuclear migration and positioning. In metazoa the NE breaks down and re-assembles around the segregated chromatids during each cell division. In this review we discuss the molecular constituents of the Caenorhabditis elegans NE and describe their role in post-mitotic NE re-formation, as well as the usefulness of C. elegans as an in vivo system for analyzing NE dynamics.
|
| Volume |
581(15)
|
| Pages |
2794-801
|
| Published |
2007-6-19
|
| DOI |
10.1016/j.febslet.2007.03.052
|
| PII |
S0014-5793(07)00325-0
|
| PMID |
17418822
|
| MeSH |
Animals
Animals, Genetically Modified
Caenorhabditis elegans / embryology
Caenorhabditis elegans / genetics
Caenorhabditis elegans / metabolism*
Caenorhabditis elegans / ultrastructure*
Caenorhabditis elegans Proteins / genetics
Caenorhabditis elegans Proteins / metabolism
Microscopy, Electron, Transmission
Mitosis
Models, Biological
Nuclear Envelope / metabolism*
Nuclear Envelope / ultrastructure*
Nuclear Pore / metabolism
Nuclear Pore / ultrastructure
Nuclear Proteins / genetics
Nuclear Proteins / metabolism
RNA Interference
|
| IF |
3.057
|
| Times Cited |
23
|
|
WOS Category
|
BIOCHEMISTRY & MOLECULAR BIOLOGY
BIOPHYSICS
CELL BIOLOGY
|
| Resource |
| C.elegans |
tm1845 |
