RRC ID 46552
Author Zhuang JJ, Hunter CP.
Title Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants.
Journal Genetics
Abstract Gene knockdown by RNA interference (RNAi) in Caenorhabditis elegans is readily achieved by feeding bacteria expressing double-stranded RNA (dsRNA). Enhanced RNAi (Eri) mutants facilitate RNAi due to their hypersensitivity to dsRNA. Here, we compare eight Eri mutants for sensitivity to ingested dsRNA, targeting a variety of tissue-specific genes.
Volume 188(1)
Pages 235-7
Published 2011-5
DOI 10.1534/genetics.111.127209
PII genetics.111.127209
PMID 21385728
PMC PMC3120140
MeSH Animals Caenorhabditis elegans / genetics* Genetic Testing Mutation / genetics* Organ Specificity / genetics* Phenotype RNA Interference* RNA, Double-Stranded / metabolism
IF 4.075
Times Cited 15
C.elegans tm1361 tm1705 tm1917 tm1860