論文 - 詳細
| RRC ID | 46552 |
|---|---|
| 著者 | Zhuang JJ, Hunter CP. |
| タイトル | Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants. |
| ジャーナル | Genetics |
| Abstract |
Gene knockdown by RNA interference (RNAi) in Caenorhabditis elegans is readily achieved by feeding bacteria expressing double-stranded RNA (dsRNA). Enhanced RNAi (Eri) mutants facilitate RNAi due to their hypersensitivity to dsRNA. Here, we compare eight Eri mutants for sensitivity to ingested dsRNA, targeting a variety of tissue-specific genes. |
| 巻・号 | 188(1) |
| ページ | 235-7 |
| 公開日 | 2011-5-1 |
| DOI | 10.1534/genetics.111.127209 |
| PII | genetics.111.127209 |
| PMID | 21385728 |
| PMC | PMC3120140 |
| MeSH | Animals Caenorhabditis elegans / genetics* Genetic Testing Mutation / genetics* Organ Specificity / genetics* Phenotype RNA Interference* RNA, Double-Stranded / metabolism |
| IF | 4.015 |
| 引用数 | 25 |
| WOS 分野 | GENETICS & HEREDITY |
| リソース情報 | |
| 線虫 | tm1361 tm1705 tm1917 tm1860 |