RRC ID 4871
Author Serikawa T, Mashimo T, Takizawa A, Okajima R, Maedomari N, Kumafuji K, Tagami F, Neoda Y, Otsuki M, Nakanishi S, Yamasaki K, Voigt B, Kuramoto T.
Title National BioResource Project-Rat and related activities.
Journal Exp Anim
Abstract In order to establish a system to facilitate the systematic collection, preservation, and provision of laboratory rats (Rattus norvegicus) and their derivates, the National BioResource Project-Rat (NBRP-Rat) was launched in July 2002. By the end of 2008, more than 500 rat strains had been collected and preserved as live animals, embryos, or sperm. These rat resources are supplied to biomedical scientists in Japan as well as in other countries. This review article introduces NBRP-Rat and highlights the phenome project, recombinant inbred strains, BAC clone libraries, and the ENU-mutant archive, named the Kyoto University Rat Mutant Archive (KURMA). The future direction of rat resources are also discussed.
Volume 58(4)
Pages 333-41
Published 2009-7-1
DOI 10.1538/expanim.58.333
PII JST.JSTAGE/expanim/58.333
PMID 19654430
MeSH Animals Animals, Laboratory Disease Models, Animal Female Genetic Predisposition to Disease Government Programs* Information Centers* International Cooperation Japan Male Phenotype Polymorphism, Genetic Rats Rats, Inbred Strains / genetics* Sex Factors
IF 1.574
Times Cited 40
WOS Category VETERINARY SCIENCES ZOOLOGY
Resource
Rats review