論文 - 詳細
| RRC ID | 56243 |
|---|---|
| 著者 | Yuan P, Pan LY, Xiong LG, Tong JW, Li J, Huang JA, Gong YS, Liu ZH. |
| タイトル | Black tea increases hypertonic stress resistance in C. elegans. |
| ジャーナル | Food Funct |
| Abstract |
Here we identified that BTE (black tea extract), within the studied concentration range, is more effective than GTE (green tea extract) in protecting C. elegans against hypertonic stress, by enhancing survival after exposure to various salts, and alleviating suffered motility loss and body shrinkage. The mechanism of such protection may be due to the ability of black tea to induce the conserved WNK/GCK signaling pathway and down-regulation of the expression levels of nlp-29. Intriguingly, black tea does not relieve hypertonicity-induced protein damage. The findings implicate the potential health benefits of black tea consumed worldwide. |
| 巻・号 | 9(7) |
| ページ | 3798-3806 |
| 公開日 | 2018-7-17 |
| DOI | 10.1039/c7fo02017a |
| PMID | 29932178 |
| MeSH | Animals Caenorhabditis elegans / drug effects* Caenorhabditis elegans / genetics Caenorhabditis elegans / physiology* Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / metabolism Camellia sinensis / chemistry* Osmotic Pressure / drug effects* Plant Extracts / chemistry Plant Extracts / pharmacology* Signal Transduction / drug effects |
| IF | 3.241 |
| 引用数 | 3 |
| リソース情報 | |
| 線虫 | |