RRC ID 6309
Author Nakase Y, Hirata A, Shimoda C, Nakamura T.
Title Ectopic overproduction of a sporulation-specific transcription factor induces assembly of prespore-like membranous compartments in vegetative cells of fission yeast.
Journal Genetics
Abstract Mei4 is a key sporulation-specific transcription factor in fission yeast. Ectopic expression of Mei4 in vegetative cells caused formation of nucleated membranous compartments, which shared common features with normal forespore membranes, thereby perturbing nuclear division. These results suggest why expression of development-specific transcription factors must be strictly controlled.
Volume 183(3)
Pages 1195-9
Published 2009-11-1
DOI 10.1534/genetics.109.106906
PII genetics.109.106906
PMID 19737749
PMC PMC2778971
MeSH Blotting, Western Cell Compartmentation Cell Division Cell Membrane / metabolism* Cell Membrane / ultrastructure Gene Expression Regulation, Fungal Green Fluorescent Proteins / genetics Green Fluorescent Proteins / metabolism Microscopy, Electron Microscopy, Fluorescence Mutation Schizosaccharomyces / cytology Schizosaccharomyces / genetics* Schizosaccharomyces / metabolism Schizosaccharomyces pombe Proteins / genetics* Schizosaccharomyces pombe Proteins / metabolism Spores, Fungal / cytology Spores, Fungal / genetics* Spores, Fungal / metabolism
IF 4.015
Times Cited 4
WOS Category GENETICS & HEREDITY
Resource
Yeast FY7456 FY6845 FY12104 FY12490