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RRC ID 65251
Author Liu YJ, McIntyre RL, Janssens GE, Williams EG, Lan J, van Weeghel M, Schomakers B, van der Veen H, van der Wel NN, Yao P, Mair WB, Aebersold R, MacInnes AW, Houtkooper RH.
Title Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30.
Journal J Cell Biol
Volume 219(6)
Published 2020-6-1
DOI 10.1083/jcb.201907067
PII 151623
PMID 32259199
PMC PMC7265311
MeSH Animals Autophagosomes / drug effects Autophagosomes / metabolism Autophagosomes / ultrastructure Basic Helix-Loop-Helix Transcription Factors / genetics Basic Helix-Loop-Helix Transcription Factors / metabolism* Caenorhabditis elegans / metabolism* Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / metabolism* Gene Ontology Longevity / genetics Longevity / physiology* Lysosomes / drug effects Lysosomes / metabolism Lysosomes / ultrastructure Microscopy, Electron, Transmission Mitochondria / genetics Mitochondria / metabolism* Mitochondrial Dynamics / drug effects* Protein Biosynthesis / drug effects* Protein Biosynthesis / physiology Proteomics RNA Interference Reproduction / physiology Signal Transduction / drug effects Signal Transduction / physiology Unfolded Protein Response / drug effects Unfolded Protein Response / genetics
Resource
C.elegans tm1108 tm1133 tm1107