論文 - 詳細
| RRC ID | 65371 |
|---|---|
| 著者 | Pérez-Jiménez MM, Monje-Moreno JM, Brokate-Llanos AM, Venegas-Calerón M, Sánchez-García A, Sansigre P, Valladares A, Esteban-García S, Suárez-Pereira I, Vitorica J, Ríos JJ, Artal-Sanz M, Carrión ÁM, Muñoz MJ. |
| タイトル | Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases. |
| ジャーナル | Nat Commun |
| 巻・号 | 12(1) |
| ページ | 49 |
| 公開日 | 2021-1-4 |
| DOI | 10.1038/s41467-020-20269-y |
| PII | 10.1038/s41467-020-20269-y |
| PMID | 33397961 |
| PMC | PMC7782729 |
| MeSH | Alzheimer Disease / enzymology* Alzheimer Disease / pathology* Animals Caenorhabditis elegans / enzymology* Caenorhabditis elegans / physiology* Caenorhabditis elegans Proteins / metabolism* Disease Models, Animal Epistasis, Genetic Gonads / metabolism Longevity* Mice Phenotype Sensory Receptor Cells / metabolism Steroids / metabolism Steryl-Sulfatase / metabolism* Sulfatases / metabolism* |
| リソース情報 | |
| 線虫 | tm6179 tm1452 tm1011 |