RRC ID 65959
Author Paudel A, Panthee S, Hamamoto H, Sekimizu K.
Title A simple artificial diet available for research of silkworm disease models.
Journal Drug Discov Ther
Abstract This study was performed with the aim of making a very simple recipe of silkworm diet for research purposes, especially screening of drug candidates. We prepared a diet containing mulberry leaves powder and soybean flour at different ratios, fed them to fifth instar silkworm larvae, and observed their growth. We selected the diet with 1:1 ratio of mulberry powder and soybean flour, named MS-11, and used for further experiments. MS-11 diet was available for oral administration of drugs in silkworm hyperglycemic model and infection model. The availability of a simple artificial diet for experiments that require feeding silkworms will enhance the use of silkworms for biological, biotechnological, and pharmacological researches.
Volume 14(4)
Pages 177-180
Published 2020-9-8
DOI 10.5582/ddt.2020.03061
PMID 32830169
MeSH Animal Feed Animals Bombyx / growth & development* Drug Evaluation, Preclinical Larva / growth & development Models, Animal Morus / chemistry* Plant Extracts / administration & dosage* Soybeans / chemistry*