RRC ID 6756
著者 Sunaga N, Monna M, Shimada N, Tsukamoto M, Kawata T.
タイトル Expression of zinc transporter family genes in Dictyostelium.
ジャーナル Int J Dev Biol
Abstract Regulation of the zinc ion concentration is physiologically important to control the activities of a variety of cellular molecules. A BLAST search against a conserved domain of known zinc transporters identified twelve putative zinc transporter family genes in the Dictyostelium genome. Phylogenetic analysis revealed the presence of three zinc transporter subfamilies in Dictyostelium. One subfamily of proteins, consisting of the ZntA-D proteins, has weak homology to the STAT3-inducible LIV-1 protein. In addition, in situ hybridization revealed that the zntA-D genes are expressed in the pstAB cells, this expression being absent in the Dd-STATa null mutant. Thus, Dd-STATa may control stalk cell differentiation through some members of the zinc transporter family genes during Dictyostelium development.
巻・号 52(4)
ページ 377-81
公開日 2008-1-1
DOI 10.1387/ijdb.072389ns
PII 072389ns
PMID 18415938
MeSH Amino Acid Sequence Animals Carrier Proteins / chemistry Carrier Proteins / classification Carrier Proteins / genetics* Dictyostelium / genetics* Dictyostelium / growth & development Gene Deletion Gene Expression Regulation, Developmental Genes, Protozoan* Hydrophobic and Hydrophilic Interactions Molecular Sequence Data Multigene Family Mutation Phylogeny Protozoan Proteins / chemistry Protozoan Proteins / classification Protozoan Proteins / genetics* Sequence Homology, Amino Acid
IF 1.105
引用数 5
WOS 分野 DEVELOPMENTAL BIOLOGY
リソース情報
細胞性粘菌 G24675 G24719 G02826 G20207