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Reference - Detail
RRC ID
70558
Author
Labana P, Dornan MH, Lafrenière M, Czarny TL, Brown ED, Pezacki JP, Boddy CN.
Title
Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria.
Journal
Cell Chem Biol
Volume
28(12)
Pages
1703-1715.e11
Published
2021-12-16
DOI
10.1016/j.chembiol.2021.07.001
PII
S2451-9456(21)00311-1
PMID
34293284
MeSH
ATPases Associated with Diverse Cellular Activities / antagonists & inhibitors*
ATPases Associated with Diverse Cellular Activities / metabolism
Anti-Bacterial Agents / chemical synthesis
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology*
Bacillus subtilis / drug effects*
Bacillus subtilis / enzymology
Cell Division / drug effects
Enzyme Inhibitors / chemical synthesis
Enzyme Inhibitors / chemistry
Enzyme Inhibitors / pharmacology*
Microbial Sensitivity Tests
Pyrroles / chemical synthesis
Pyrroles / chemistry
Pyrroles / pharmacology
Spiro Compounds / chemical synthesis
Spiro Compounds / chemistry
Spiro Compounds / pharmacology
Streptomyces / chemistry
IF
6.762
Resource
Prokaryotes B. subtilis