Reference - Detail
| RRC ID | 70745 |
|---|---|
| Author | Moussian B, Casadei N. |
| Title | Identification and Functional Characterization of Argonaute (Ago) Proteins in Insect Genomes. |
| Journal | Methods Mol Biol |
| Abstract |
RNA processing is a vital process in all organisms. In eukaryotes, the RNA induced silencing complex (RISC) mediates this function during development and physiological processes and, at least in arthropods, during RNA-viral infections. Argonaute-like RNA-binding proteins are central components of this complex. RNA-based insecticides are gaining more and more a central role in pest control. Understanding of the underlying molecular mechanisms including Ago-like proteins is crucial in designing powerful, species-specific and environmental-friendly insecticides. This chapter describes a protocol for identification and genetic functional analyses of insect Ago-like proteins in the fruit fly Drosophila melanogaster that serves as a living test tube. |
| Volume | 2360 |
| Pages | 9-17 |
| Published | 2022-1-1 |
| DOI | 10.1007/978-1-0716-1633-8_2 |
| PMID | 34495503 |
| MeSH | Animals Argonaute Proteins / genetics Argonaute Proteins / metabolism Drosophila / metabolism Drosophila Proteins / genetics Drosophila melanogaster / genetics Drosophila melanogaster / metabolism Genome, Insect* Insecticides RNA RNA Interference RNA-Induced Silencing Complex / metabolism |
| Altmetric score |
オルトメトリクス指標項目
|
| Total number of mentions | 0 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Drosophila | |