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Species Resource Title
C.elegans tm1200 , tm116 , tm116102 HRDE-2 drives small RNA specificity for the nuclear Argonaute protein HRDE-1.
Drosophila D. pseudoobscura (k-s12), , D. eugracilis (E-18102), , D. mojavensis (k-s13) The absence of core piRNA biogenesis factors does not impact efficient transposon silencing in Drosophila
Arabidopsis / Cultured plant cells, genes pdx02732 Molecular modeling and interaction between Arabidopsis sulfite oxidase and the GW motif of Turnip crinkle virus coat protein.
C.elegans tm872 A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing.
C.elegans tm1163 TRIM-NHL protein, NHL-2, modulates cell fate choices in the C. elegans germ line.
C.elegans tm4477 , tm869 pre-piRNA trimming and 2'-O-methylation protect piRNAs from 3' tailing and degradation in C. elegans.
C.elegans tm872 , tm1301 Dual roles for piRNAs in promoting and preventing gene silencing in C. elegans.
C.elegans tm872 , tm1200 , tm1276 HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans.
C.elegans tm2723 PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans.
C.elegans tm1200 , tm892 piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development.
Arabidopsis / Cultured plant cells, genes rpc00001 The mechanisms of siRNA selection by plant Argonaute proteins triggering DNA methylation.
Drosophila Identification and Functional Characterization of Argonaute (Ago) Proteins in Insect Genomes.
Drosophila DGRC#124205 , DGRC#126282 Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation.
Human and Animal Cells 409B2(HPS0076) A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation.
Human and Animal Cells KGN(RCB1154) An alternative miRISC targets a cancer-associated coding sequence mutation in FOXL2.
Human and Animal Cells LK-2(RCB1970) , RERF-LC-AI(RCB0444) , EBC-1(RCB1965) , LC-1/sq-SF(RCB0438) Recruitment of KMT2C/MLL3 to DNA Damage Sites Mediates DNA Damage Responses and Regulates PARP Inhibitor Sensitivity in Cancer.
C.elegans tm1614 , tm1200 , tm1414 , tm2686 , tm1120 Intrinsically disordered protein PID-2 modulates Z granules and is required for heritable piRNA-induced silencing in the Caenorhabditis elegans embryo.
C.elegans A Conserved NRDE-2/MTR-4 Complex Mediates Nuclear RNAi in Caenorhabditis elegans.
Arabidopsis / Cultured plant cells, genes pst00853 Dual control of ROS1-mediated active DNA demethylation by DNA damage-binding protein 2 (DDB2).
C.elegans tm1200 , tm1860 Neuronal Small RNAs Control Behavior Transgenerationally.