RRC ID 78890
Author Gwénaëlle Bontonou, Bastien Saint-Leandre, Tane Kafle, Tess Baticle, Afrah Hassan, Juan Antonio Sánchez-Alcañiz, J. Roman Arguello
Title Evolution of chemosensory tissues and cells across ecologically diverse Drosophilids
Journal Nature Communications
Abstract Chemosensory tissues exhibit significant between-species variability, yet the evolution of gene expression and cell types underlying this diversity remain poorly understood. To address these questions, we conducted transcriptomic analyses of five chemosensory tissues from six Drosophila species and integrated the findings with single-cell datasets. While stabilizing selection predominantly shapes chemosensory transcriptomes, thousands of genes in each tissue have evolved expression differences. Genes that have changed expression in one tissue have often changed in multiple other tissues but at different past epochs and are more likely to be cell type-specific than unchanged genes. Notably, chemosensory-related genes have undergone widespread expression changes, with numerous species-specific gains/losses including novel chemoreceptors expression patterns. Sex differences are also pervasive, including a D. melanogaster-specific excess of male-biased expression in sensory and muscle cells in its forelegs. Together, our analyses provide new insights for understanding evolutionary changes in chemosensory tissues at both global and individual gene levels.
Volume 15
Published 2024-2-5
DOI 10.1038/s41467-023-44558-4
PMID 38316749
PMC PMC10844241
MeSH Animals Drosophila / genetics Drosophila / metabolism Drosophila Proteins* / genetics Drosophila Proteins* / metabolism Drosophila melanogaster* / genetics Drosophila melanogaster* / metabolism Evolution, Molecular Female Gene Expression Profiling Male Phylogeny Transcriptome
IF 12.121
Drosophila D. suzukii (Kyorin, K-AWA036)