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  • Search Condition : Filter (MeSH = Aging / genetics)
Species Resource Title
Drosophila DGRC#112001 Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
Human and Animal Cells 293T(RCB2202) Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Human and Animal Cells MC3T3-E1(RCB1126) Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice.
Human and Animal Cells MC3T3-E1(RCB1126) 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts.
C.elegans tm2993 , tm1445 DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes.
C.elegans tm985 , tm1978 , tm4450 Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.
C.elegans tm1452 The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity.
Drosophila Effect of heterochromatin stability on intestinal stem cell aging in Drosophila.
Prokaryotes E. coli Folate Acts in E. coli to Accelerate C. elegans Aging Independently of Bacterial Biosynthesis.
C.elegans tm1011 , tm2457 Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7.
C.elegans tm5755 , tm4417 , tm1954 , tm4498 , tm1978 Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans.
C.elegans tm2482 Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans.
C.elegans tm1966 C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span.
Human and Animal Cells DJM-1(RCB0736) Aberrant DNA Methylation in Keratoacanthoma.
C.elegans tm1944 DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
Arabidopsis / Cultured plant cells, genes pda06002 A Role for TIC55 as a Hydroxylase of Phyllobilins, the Products of Chlorophyll Breakdown during Plant Senescence.
C.elegans tm3464 The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration.
C.elegans NA Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans.
C.elegans tm4607 Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging.
C.elegans tm4355 The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans.