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  • Search Condition : Filter (MeSH = Aging / metabolism)
Species Resource
Drosophila 2107R-2 Glial β-oxidation regulates Drosophila energy metabolism.
Drosophila DGRC#103877 Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.
Drosophila DGRC#109027 Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila.
C.elegans tm2895 , tm2100 , tm2525 , tm2535 Deletion of the four phospholipid hydroperoxide glutathione peroxidase genes accelerates aging in Caenorhabditis elegans.
Drosophila 5680R-2 Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.
Zebrafish RIKEN WT Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.
DNA material ETR103 Human Egr-1 cDNA , TPA early response gene (RDB01198) Angiotensin II stimulates platelet-derived growth factor-B chain expression in newborn rat vascular smooth muscle cells and neointimal cells through Ras, extracellular signal-regulated protein kinase, and c-Jun N-terminal protein kinase mechanisms.
Human and Animal Cells Increasing participation of sclerostin in postnatal bone development, revealed by three-dimensional immunofluorescence morphometry.
Rats F344.OLETF-(D14Rat23-D14Rat12)/Tj(strainID=87) Proteomic analysis of a diabetic congenic rat identified age-dependent alteration of an acidic protein.
C.elegans SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat.
Drosophila DGRC#105467 A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
Mice B6.129S-Atg5<tm1Myok>(RBRC02975) Cardioprotection and lifespan extension by the natural polyamine spermidine.
C.elegans tm1954 , tm4498 , tm2580 , tm1978 MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
C.elegans tm1512 , tm1555 Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans.
C.elegans tm4547 , tm4529 , tm4627 , tm4924 Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
C.elegans NA Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans.
C.elegans tm3464 The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration.
C.elegans tm1349 A photoconvertible reporter of the ubiquitin-proteasome system in vivo.
C.elegans tm1944 Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
C.elegans tm3411 , tm2256 Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response.