• 49 Hits
  • 検索条件 : 絞込み (MeSH = Aging / metabolism)
生物種 リソース名 タイトル
線虫 tm1978 S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
線虫 tm2543 , tm2134 , tm1842 , tm2181 , tm2644 , tm1937 , tm3655 Meiotic dysfunction accelerates somatic aging in Caenorhabditis elegans.
線虫 Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans.
実験動物マウス RBRC06344 , RBRC03390 , RBRC03418 Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
酵母 BY5701, Strain alias: SH5701, W303-1A S-adenosyl-L-homocysteine extends lifespan through methionine restriction effects.
ショウジョウバエ DGRC#104863 A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.
ショウジョウバエ DGRC#111923 Neuroglian regulates Drosophila intestinal stem cell proliferation through enhanced signaling via the epidermal growth factor receptor.
線虫 tm1291 , tm2505 Extracellular proteostasis prevents aggregation during pathogenic attack.
ヒト・動物細胞 10T1/2(RCB0247) Selective Inhibition of ADAM17 Efficiently Mediates Glycoprotein Ibα Retention During Ex Vivo Generation of Human Induced Pluripotent Stem Cell-Derived Platelets.
ショウジョウバエ DGRC#112001 , DGRC#109126 Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine.
実験動物マウス RBRC06334 Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
ヒト・動物細胞 MC3T3-E1(RCB1126) 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts.
線虫 tm1406 , tm1444 GABA receptors differentially regulate life span and health span in C. elegans through distinct downstream mechanisms.
ヒト・動物細胞 RAW 264(RCB0535) MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.
ヒト・動物細胞 MG6(RCB2403) Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.
線虫 tm2182 , tm3410 , tm5782 , tm420 SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat.
遺伝子材料 mouse Period2 (-2.8 - +0.1 kb)_luciferase/pENTR-1A (RDB15083) , human Period3 (-3.1 - +0.2 kb)_luciferase/pENTR-1A (RDB15084) , human Bmal1 (-1.7 - +0.1 kb)_luciferase/pENTR-1A (RDB15085). A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans.
線虫 tm3886 Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans.
線虫 tm1011 , tm1231 , tm2182 , tm331 , tm420 Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.
実験動物マウス RBRC02975 Cardioprotection and lifespan extension by the natural polyamine spermidine.