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  • Search Condition : Filter (MeSH = Aging / metabolism)
Species Resource
Human and Animal Cells MC3T3-E1(RCB1126) 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts.
C.elegans NA GABA receptors differentially regulate life span and health span in C. elegans through distinct downstream mechanisms.
Human and Animal Cells RAW 264(RCB0535) MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.
Human and Animal Cells MG6(RCB2403) Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.
C.elegans tm2182 , tm3410 , tm5782 , tm420 SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat.
DNA material mouse Period2 (-2.8 - +0.1 kb)_luciferase/pENTR-1A (RDB15083) , human Period3 (-3.1 - +0.2 kb)_luciferase/pENTR-1A (RDB15084) , human Bmal1 (-1.7 - +0.1 kb)_luciferase/pENTR-1A (RDB15085). A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans.
C.elegans tm3886 Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans.
C.elegans tm1011 , tm1231 , tm2182 , tm331 , tm420 Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.
Mice B6.129S-Atg5<tm1Myok>(RBRC02975) Cardioprotection and lifespan extension by the natural polyamine spermidine.
Drosophila DGRC#105467 A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
Drosophila 10814R-2 , 10814R-4 Genes Related to Fatty Acid β-Oxidation Play a Role in the Functional Decline of the Drosophila Brain with Age.
C.elegans tm1944 Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
C.elegans tm1349 A photoconvertible reporter of the ubiquitin-proteasome system in vivo.
C.elegans tm3464 The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration.
C.elegans NA Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans.
C.elegans tm4547 , tm4529 , tm4627 , tm4924 Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
C.elegans tm1512 , tm1555 Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans.
C.elegans tm1954 , tm4498 , tm2580 , tm1978 MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability.
C.elegans tm4272 A systematic analysis of protein palmitoylation in Caenorhabditis elegans.
C.elegans tm3411 , tm2256 Caenorhabditis elegans OSM-11 signaling regulates SKN-1/Nrf during embryonic development and adult longevity and stress response.