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  • Search Condition : Filter (MeSH = Chromones / pharmacology)
Species Resource
General Microbes JCM 1612 Candida albicans and Candida parapsilosis rapidly up-regulate galectin-3 secretion by human gingival epithelial cells.
C.elegans tm1888 Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.
Medaka OK-Cab (MT830) , Qurt(MT828) Migration of mesenchymal cell fated to blastema is necessary for fish fin regeneration.
Cellular slime molds S00007 Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium.
Human and Animal Cells RERF-LC-AI(RCB0444) , IA-LM(RCB0554) , WA-hT(RCB2279) Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.
Human and Animal Cells Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells.
Human and Animal Cells Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma.
Human and Animal Cells Exhaustive exercise increases the TNF-α production in response to flagellin via the upregulation of toll-like receptor 5 in the large intestine in mice.
Human and Animal Cells RCN-9 (RCB0511) Cysteinyl leukotriene receptor antagonists inhibit tumor metastasis by inhibiting capillary permeability.
Human and Animal Cells PANC-1 (RCB2095) , NOR-P1 (RCB2139) , PK-45H (RCB1973) , PK-1 (RCB1972) , PK-59 (RCB1901) , MIA Paca2 (RCB2094) Insulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer.
Human and Animal Cells A172 (RCB2530) Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
Human and Animal Cells F-36P (RCB0775) Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells.
Human and Animal Cells Acetylcholinesterase inhibitors attenuate angiogenesis.
Human and Animal Cells Regulation of DNA damage response and cell cycle in radiation-resistant HL60 myeloid leukemia cells.
Human and Animal Cells KP4 Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines.
Human and Animal Cells ATDC5 , 10T1/2 Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling.
Human and Animal Cells MC3T3-E1 Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.
Human and Animal Cells Macrophage inflammatory protein-1alpha (MIP-1alpha) enhances a receptor activator of nuclear factor kappaB ligand (RANKL) expression in mouse bone marrow stromal cells and osteoblasts through MAPK and PI3K/Akt pathways.
Human and Animal Cells Histidine-rich glycoprotein and concanavalin A synergistically stimulate the phosphatidylinositol 3-kinase-independent signaling pathway in leukocytes leading to increased cell adhesion and changes in cell morphology.
Human and Animal Cells Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase.