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Species Resource Title
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells MCF7(RCB1904) , MRC-5(RCB0218) 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced Histone Acetylation via α7nAChR-Mediated PI3K/Akt Activation and Its Impact on γ-H2AX Generation.
Human and Animal Cells MDCK(RCB0995) Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K.
Human and Animal Cells A549 Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
Human and Animal Cells MC3T3-E1(RCB1126) Effects of iguratimod on glucocorticoid-induced disorder of bone metabolism in vitro.
Human and Animal Cells A431(RCB0202) , RAW 264(RCB0535) Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor.
Human and Animal Cells ATDC5(RCB0565) Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.
Human and Animal Cells RAW 264(RCB0535) Involvement of interleukin‑23 induced by Porphyromonas endodontalis lipopolysaccharide in osteoclastogenesis.
Human and Animal Cells A549 ZO-2 Suppresses Cell Migration Mediated by a Reduction in Matrix Metalloproteinase 2 in Claudin-18-Expressing Lung Adenocarcinoma A549 Cells.
Human and Animal Cells Ca9-22(RCB1976) , HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) Quantitative Structure-Cytotoxicity Relationship of 2-Arylazolylchromones and 2-Triazolylchromones.
Human and Animal Cells CACO-2(RCB0988) Flavonol glycosides of Rosa multiflora regulates intestinal barrier function through inhibiting claudin expression in differentiated Caco-2 cells.
DNA material Genome Network Project Human cDNA , IRAL021H13 (HGY088581) , IRAK004A12 (HGX001612) S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein.
Human and Animal Cells HSC-3(RCB1975) , HSC-4(RCB1902) Characterization of KIF11 as a novel prognostic biomarker and therapeutic target for oral cancer.
Human and Animal Cells RERF-LC-AI(RCB0444) , IA-LM(RCB0554) , WA-hT(RCB2279) Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.
C.elegans tm1888 Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.
Human and Animal Cells RAW 264(RCB0535) , CACO-2(RCB0988) Exhaustive exercise increases the TNF-α production in response to flagellin via the upregulation of toll-like receptor 5 in the large intestine in mice.
Human and Animal Cells C6(RCB2854) Harmine hydrochloride inhibits Akt phosphorylation and depletes the pool of cancer stem-like cells of glioblastoma.
Human and Animal Cells HL60(RCB0041) Regulation of DNA damage response and cell cycle in radiation-resistant HL60 myeloid leukemia cells.
Human and Animal Cells C2C12(RCB0987) Acetylcholinesterase inhibitors attenuate angiogenesis.
Human and Animal Cells HuH-6(RCB1367) , Hep G2 Insulin-like growth factor (IGF)-II regulates CCAAT/enhancer binding protein alpha expression via phosphatidyl-inositol 3 kinase in human hepatoblastoma cell lines.