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  • 検索条件 : 絞込み (MeSH = Cyclin-Dependent Kinase 4 / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 LACF-NaNaII(RCB2320) Expression of human cell cycle regulators in the primary cell line of the African savannah elephant (loxodonta africana) increases proliferation until senescence, but does not induce immortalization.
遺伝子材料 , ヒト・動物細胞 pENTR4-H1tetOx1 (RDB07916) , THP-1(RCB1189) Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (REB04393) Primary and immortalized cell lines derived from the Amami rabbit (Pentalagus furnessi) and evolutionally conserved cell cycle control with CDK4 and Cyclin D1.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).
ヒト・動物細胞 Ca9-22(RCB1976) , HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) , SAS(RCB1974) TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase.
ショウジョウバエ 4006R-3 Spatial Activation of TORC1 Is Regulated by Hedgehog and E2F1 Signaling in the Drosophila Eye.
遺伝子材料 CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.
遺伝子材料 AxCANCre (RDB01748) The CDKN1B-RB1-E2F1 pathway protects mouse spermatogonial stem cells from genomic damage.
ヒト・動物細胞 K562 Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation.
遺伝子材料 CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase.
遺伝子材料 CSII-CMV-RfA (RDB04386) , CSII-EF-RfA (RDB04387). A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
遺伝子材料 CSII-EF-MCS (RDB04378) Androgen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells.
ヒト・動物細胞 GE1(RCB1709) Establishment of human dental epithelial cell lines expressing ameloblastin and enamelin by transfection of hTERT and cdk4 cDNAs.
遺伝子材料 Ax1w1 (RDB01746) Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6.