• 90 Hits
  • 検索条件 : 絞込み (MeSH = Down-Regulation / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 KGN(RCB1154) Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction.
ヒト・動物細胞 HUDEP-2(RCB4557) , HUDEP-1(RCB4556) ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin.
ヒト・動物細胞 SHP1^(-) DT40(RCB1466) , SHP1^(-)/SHP2^(-) DT40(RCB1501) , SHP2^(-) DT40(RCB1502) , SHIP^(-) DT40(RCB1465) Src homology 2 domain-containing protein-tyrosine phosphatases, SHP-1 and SHP-2, are required for platelet endothelial cell adhesion molecule-1/CD31-mediated inhibitory signaling.
ヒト・動物細胞 JHOS-2(RCB1521) , JHOS-4(RCB1678) , NIH:OVCAR-3(RCB2135) The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma.
ヒト・動物細胞 HuH-7(RCB1366) , Li-7(RCB1941) , Hep G2(RCB1648) Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules.
ヒト・動物細胞 StromaNKtert(RCB2350) The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma.
病原細菌 RIMD 2210633 S-nitrosylation-mediated activation of a histidine kinase represses the type 3 secretion system and promotes virulence of an enteric pathogen.
ヒト・動物細胞 H-1(AES0001) Identification of RNA biomarkers for chemical safety screening in mouse embryonic stem cells using RNA deep sequencing analysis.
ヒト・動物細胞 PC-9(RCB4455) Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator.
ヒト・動物細胞 UE7T-13(RCB2161) Cellular Model of Alzheimer's Disease: Aβ1-42 Peptide Induces Amyloid Deposition and a Decrease in Topo Isomerase IIβ and Nurr1 Expression.
ヒト・動物細胞 RAW 264(RCB0535) CaMKII(δ) regulates osteoclastogenesis through ERK, JNK, and p38 MAPKs and CREB signalling pathway.
ヒト・動物細胞 MKN45(RCB1001) , MKN74(RCB1002) MiR-129-5p induces cell cycle arrest through modulating HOXC10/Cyclin D1 to inhibit gastric cancer progression.
ヒト・動物細胞 Huh-7 RNA Editing Modulates Human Hepatic Aryl Hydrocarbon Receptor Expression by Creating MicroRNA Recognition Sequence.
ヒト・動物細胞 PANC-1(RCB2095) LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer.
ヒト・動物細胞 ST2(RCB0224) Diabetic osteopenia by decreased β-catenin signaling is partly induced by epigenetic derepression of sFRP-4 gene.
ヒト・動物細胞 201B7(HPS0063) Suppression of Lefty expression in induced pluripotent cancer cells.
ヒト・動物細胞 SAS(RCB1974) , HSC-3(RCB1975) , HSC-4(RCB1902) A novel function of EpCAM in oral squamous cell carcinoma cells under anchorage-independent conditions.
ヒト・動物細胞 A549(RCB0098) CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development.
ツメガエル・イモリ The AP-1 transcription factor JunB functions in Xenopus tail regeneration by positively regulating cell proliferation.
ヒト・動物細胞 HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) , Ca9-22(RCB1976) , HO-1-u-1(RCB2102) , SAS(RCB1974) Tspan15 plays a crucial role in metastasis in oral squamous cell carcinoma.