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  • Search Condition : Filter (MeSH = Endodeoxyribonucleases / metabolism)
Species Resource Title
Human and Animal Cells 293T(RCB2202) Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) Polη, a Y-family translesion synthesis polymerase, promotes cellular tolerance of Myc-induced replication stress.
C.elegans tm3468 The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans.
Human and Animal Cells C2C12(RCB0987) Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway.
C.elegans tm1842 The Caenorhabditis elegans WRN helicase promotes double-strand DNA break repair by mediating end resection and checkpoint activation.
Yeast The histone variant H2A.Z promotes initiation of meiotic recombination in fission yeast.
Arabidopsis / Cultured plant cells, genes pda12225 , pda04013 Systematic deletion of the ER lectin chaperone genes reveals their roles in vegetative growth and male gametophyte development in Arabidopsis.
C.elegans tm1125 , tm1227 , tm1458 , tm1145 MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells.
C.elegans tm1524 , tm1842 , tm1145 COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining.
C.elegans tm4374 , tm1842 , tm853 Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy.
Prokaryotes E. coli JW1850-2(Keio) , JW3627-1(Keio) , JW1852-1(Keio) Analysis of RuvABC and RecG involvement in the escherichia coli response to the covalent topoisomerase-DNA complex.
Japanese macaques DNA methylation and methyl-binding proteins control differential gene expression in distinct cortical areas of macaque monkey.
Drosophila 7780R-3 Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif.
Mice RBRC01725 STING manifests self DNA-dependent inflammatory disease.
C.elegans slx-1(tm2644) , brc-2(tm1086) , him-18(tm2181) SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.
C.elegans tm890 The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development.
C.elegans tm1415 Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation.
Prokaryotes E. coli ME8083 , ME8680(E486) Nucleotide excision repair and homologous recombination systems commit differentially to the repair of DNA-protein crosslinks.
Silkworms Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies.
Yeast genomic library Separase-mediated cleavage of cohesin at interphase is required for DNA repair.