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  • Search Condition : Filter (MeSH = Endosomes / metabolism*)
Species Resource Title
C.elegans tm1595 , tm5356 , tm847 , tm2423 , tm2404 , tm3643 , tm1320 SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
C.elegans tm10626 PDZD-8 and TEX-2 regulate endosomal PI(4,5)P2 homeostasis via lipid transport to promote embryogenesis in C. elegans.
DNA material pMRX-IP-GFP-STX17 (RDB19636) , pMRX-IP-GFP-SNAP29 (RDB19638) , pMRX-IP-GFP-VAMP7 (RDB19639) , pMRX-IP-GFP-VAMP8 (RDB19640) , p3xFLAG-CMV10-Stx17 (RDB19761) , p3xFLAG-CMV10-SNAP29 (RDB19765) , p3xFLAG-CMV10-VAMP7 (RDB19778) , pMRXIP GFP-Stx7 (RDB19779) , pMRXIP-GFP-Stx18 (RDB19792) , pMRXIP-GFP-Stx17TM (RDB19793) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
Human and Animal Cells HuH-7(RCB1366) A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery.
Human and Animal Cells HeLa(RCB0007) , K562 Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes.
DNA material pEF-FLAG-mouse myosin Vb-tail (RDB15286) Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
Mice RBRC06240 Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis.
C.elegans tm2526 , tm2663 An EHBP-1-SID-3-DYN-1 axis promotes membranous tubule fission during endocytic recycling.
Human and Animal Cells A431(RCB0202) , HeLa(RCB0007) , 293(RCB1637) Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation.
Human and Animal Cells Atg5^(-/-)MEF(RCB2711) Sucrose induces vesicle accumulation and autophagy.
C.elegans tm1447 , tm847 , tm1736 , tm331 , tm2526 Revealing Functional Crosstalk between Distinct Bioprocesses through Reciprocal Functional Tests of Genetically Interacting Genes.
C.elegans tm1320 , tm5356 SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
C.elegans tm2523 , tm1447 RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
Human and Animal Cells HeLa Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.
Yeast FY23692 , FY23684 Ent3 and GGA adaptors facilitate diverse anterograde and retrograde trafficking events to and from the prevacuolar endosome.
Drosophila DGRC#102398 WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.
Drosophila 10144R-1 , 7891R-2 , DGRC#141824 , DGRC#141970 Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt.
Human and Animal Cells HeLa SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
DNA material pmStr-C1-Rab10 (RDB17221) , pMRX-puro-EGFP-Rab5A (RDB17222) , pMRX-puro-EGFP-Rab10 (RDB17223) , pMRX-puro-EGFP-Rab13 (RDB17224) , pMRX-puro-EGFP-Rab17 (RDB17225) , pMRX-puro-EGFP-Rab21 (RDB17226) , pMRX-puro-EGFP-Rab22A (RDB17227) , pMRX-puro-EGFP-Rab23 (RDB17228) , pMRX-bsr-mStr-EMTB (RDB17229) , pEGFP-C1-KIF13A-tail (RDB17230) , ... Rab10 regulates tubular endosome formation through KIF13A and KIF13B motors.
DNA material pEF-T7-mALS2 (RDB17219) , pEF-T7-mALS2-D1593A (RDB17220). Rab5 activation on macropinosomes requires ALS2, and subsequent Rab5 inactivation through ALS2 detachment requires active Rab7.