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  • Search Condition : Filter (MeSH = Endosomes / metabolism*)
Species Resource
C.elegans tm2949 MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation.
C.elegans snx-1(tm0847) , tm847 , tm857 Regulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8.
Drosophila Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes.
Yeast Genome DNA clones Role of the Small GTPase Rho3 in Golgi/Endosome trafficking through functional interaction with adaptin in Fission Yeast.
Arabidopsis / Cultured plant cells, genes pda04478 EXPO, an exocyst-positive organelle distinct from multivesicular endosomes and autophagosomes, mediates cytosol to cell wall exocytosis in Arabidopsis and tobacco cells.
Yeast Genome DNA clones Sip1, a conserved AP-1 accessory protein, is important for Golgi/endosome trafficking in fission yeast.
C.elegans tm2241 TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans.
Yeast pNHK53 , pMK43 TRAPPIII is responsible for vesicular transport from early endosomes to Golgi, facilitating Atg9 cycling in autophagy.
C.elegans RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes.
C.elegans Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
Drosophila WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.
DNA material pco12 EGFR (RDB01276) , CSII-EF-MCS (RDB04378). ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
C.elegans tm2241 The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.
C.elegans tm2056 , tm1320 , tm1595 , tm1523 A TOCA/CDC-42/PAR/WAVE functional module required for retrograde endocytic recycling.
C.elegans tm1443 SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans.
C.elegans tm3489 Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during Caenorhabditis elegans development.
C.elegans tm1125 Loss of the Sec1/Munc18-family proteins VPS-33.2 and VPS-33.1 bypasses a block in endosome maturation in Caenorhabditis elegans.
C.elegans tm847 , tm3790 , tm1320 Derlin-dependent retrograde transport from endosomes to the Golgi apparatus.
C.elegans tm1595 , tm2241 , tm1320 , tm847 , tm1963 , tm1910 Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.
DNA material pEF-LRRK2-FLAG-His (RDB13973) , pEF-HERC2 (RDB13974) , pEF-NEURL4 (RDB13975) , pEGFP-C-HERC2 (RDB13976) , pEGFP-C-NEURL4 (RDB13977) , pcDNA3-NEURL4-FLAG-His (RDB13978) , pcDNA3-FLAG-HERC2 (RDB13979). The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.