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Species Resource Title
Mice RBRC02182 MFN1 and MFN2 Are Dispensable for Sperm Development and Functions in Mice.
Lotus / Glycine pUB-GWS-GFP , pUB-GFP SPIKE1 Activates the GTPase ROP6 to Guide the Polarized Growth of Infection Threads in Lotus japonicus.
Human and Animal Cells 253G1(HPS0002) Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells.
C.elegans tm3425 , tm2508 The RBG-1-RBG-2 complex modulates autophagy activity by regulating lysosomal biogenesis and function in C. elegans.
Zebrafish Tg(zfRh1-3.7B:EGFP) The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance.
Human and Animal Cells 253G1(HPS0002) 5-Fluorouracil inhibits neural differentiation via Mfn1/2 reduction in human induced pluripotent stem cells.
Prokaryotes E. coli (p)ppGpp-dependent and -independent pathways for salt tolerance in Escherichia coli.
Drosophila Stratum recruits Rab8 at Golgi exit sites to regulate the basolateral sorting of Notch and Sanpodo.
Human and Animal Cells 253G1(HPS0002) Tributyltin induces mitochondrial fission through Mfn1 degradation in human induced pluripotent stem cells.
DNA material pEF-T7-mouse Atg5 (RDB15374) , pEF-T7-mouse Atg12 (RDB15375) , pEF-T7-mouse Atg16L1gamma (RDB15376) , pEGFP-C1-mouse Rab33A (RDB15378) , pEGFP-C1-mouse Rab33B (RDB15379) , pEGFP-C1-mouse Rab33B-Q92L (RDB15380) , pEGFP-C1-mouse Rab33B-T47N (RDB15381). Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation.
C.elegans tm2504 The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans.
C.elegans tm1862 Manipulation of behavioral decline in Caenorhabditis elegans with the Rag GTPase raga-1.
C.elegans tm3203 , tm2916 , tm2926 , tm3214 Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans.
C.elegans tm2388 , tm1125 The balance between capture and dissociation of presynaptic proteins controls the spatial distribution of synapses.
Human and Animal Cells HeLa(RCB0007) Dynamin is involved in human epithelial cell vacuolation caused by the Helicobacter pylori-produced cytotoxin VacA.
Lotus / Glycine LORE1 P0665 Lotus japonicus clathrin heavy Chain1 is associated with Rho-Like GTPase ROP6 and involved in nodule formation.
Prokaryotes E. coli ASKA library RsgA releases RbfA from 30S ribosome during a late stage of ribosome biosynthesis.
C.elegans tm2313 , tm2526 , tm1447 RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate.
Mice RBRC02591 The GTPase-activating protein GIT2 protects against colitis by negatively regulating Toll-like receptor signaling.
DNA material pRS316-SEC16 (RDB08769) , pYS28-E52 (RDB08664) , pYS6-7 (RDB08766) , pYS6 (RDB08767) , pYS25 (RDB08768) , pSKY2-2 (RDB08770) Sed4p functions as a positive regulator of Sar1p probably through inhibition of the GTPase activation by Sec23p.