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論文 - 一覧

  • 14 Hits
  • 検索条件 : 絞込み (MeSH = Gain of Function Mutation)
生物種 リソース名 タイトル
ヒト・動物細胞 TE-1(RCB1894) , TE-5(RCB1949) , TE-6(RCB1950) , TE-8(RCB2098) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) , TE-15(RCB1951) Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma.
ヒト・動物細胞 HUDEP-2(RCB4557) A novel gain-of-function PIP4K2A mutation elevates the expression of β-globin and aggravates the severity of α-thalassemia.
ヒト・動物細胞 ME-180(RCB2160) , Ca Ski(RCB1947) Targeting the mutant PIK3CA gene by DNA-alkylating pyrrole-imidazole polyamide in cervical cancer.
シロイヌナズナ / 植物培養細胞・遺伝子 pst00216 TIC236 gain-of-function mutations unveil the link between plastid division and plastid protein import.
線虫 tm5030 , tm6659 Mutation of daf-2 extends lifespan via tissue-specific effectors that suppress distinct life-limiting pathologies.
線虫 tm2235 Synaptic Protein Degradation Controls Sexually Dimorphic Circuits through Regulation of DCC/UNC-40.
線虫 tm783 ROS regulation of RAS and vulva development in Caenorhabditis elegans.
線虫 tm1036 The Snail transcription factor CES-1 regulates glutamatergic behavior in C. elegans.
ヒト・動物細胞 Li-7(RCB1941) TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
ショウジョウバエ The Clathrin adaptor AP-1 and Stratum act in parallel pathways to control Notch activation in Drosophila sensory organ precursors cells.
線虫 tm4533 The hypoxia-response pathway modulates RAS/MAPK-mediated cell fate decisions in Caenorhabditis elegans.
線虫 tm1227 , tm294 Active chromatin marks drive spatial sequestration of heterochromatin in C. elegans nuclei.
線虫 tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
線虫 tm3464 Genetic Suppression of Basement Membrane Defects in Caenorhabditis elegans by Gain of Function in Extracellular Matrix and Cell-Matrix Attachment Genes.