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  • Search Condition : Filter (MeSH = Gene Knock-In Techniques)
Species Resource
Mice A high-speed congenic strategy using first-wave male germ cells.
Mice B6.129S6-Gcg<tm1Yhys> (RBRC02831) Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides.
Mice B6C3F1-Tg(CAG-EGFP)CX-FM038Osb(RBRC00980) DA-Raf-dependent inhibition of the Ras-ERK signaling pathway in type 2 alveolar epithelial cells controls alveolar formation.
Mice B6.Cg-Tg(CAG-Cre)CZ-MO2Osb(RBRC01828) New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.
Mice B6.Cg-Tg(FucciS/G2/M)#504Bsi Tg(FucciG1)#596Bsi(RBRC02892) Oscillatory control of factors determining multipotency and fate in mouse neural progenitors.
C.elegans tm3464 Genetic Suppression of Basement Membrane Defects in Caenorhabditis elegans by Gain of Function in Extracellular Matrix and Cell-Matrix Attachment Genes.
DNA material T7-NLS hCas9-pA (RDB13130) , pCAGGS (RDB08938) ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes.
Drosophila O-fucose monosaccharide of Drosophila Notch has a temperature-sensitive function and cooperates with O-glucose glycan in Notch transport and Notch signaling activation.
Mice C57BL/6N-Sqstm1/Rbrc(RBRC03941) Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.
Mice B6.Cg-Tg(CAG-Cre)CZ-MO2Osb(RBRC01828) Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
DNA material CSII-EF-Venus (RDB05552) CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells.
Rats F344-Il2rgem2Kyo (strainID=979) Generation of scaffoldless hyaline cartilaginous tissue from human iPSCs.
Mice GFP-LC3#53(RBRC00806) The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Rats W-Rosa26em1(CAG-GFP)Kyo (StrainID=1186) ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes.
DNA material pDll1-Ub-Fluc (RDB14127) , pDll1-Fluc (RDB14128). Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.
Human and Animal Cells CHO-K1(RCB0285) Biased genome editing using the local accumulation of DSB repair molecules system.
Human and Animal Cells TT2(AES0014) Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.
Human and Animal Cells GS-DG1(AES0002) , Mvh-Venus GS(AES0196) Generating Genetically Engineered Mice Using a Spermatogonial Stem Cell-Mediated Method.
Human and Animal Cells Loss of RUNX1/AML1 arginine-methylation impairs peripheral T cell homeostasis.
Human and Animal Cells MRC-5 SV1 TG1(RCB0207) Transgene integration into the human AAVS1 locus enhances myosin II-dependent contractile force by reducing expression of myosin binding subunit 85.