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  • Search Condition : Filter (MeSH = Gene Knock-In Techniques)
Species Resource Title
Human and Animal Cells ST2(RCB0224) BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with Acvr2b.
DNA material Genome Network Project Human cDNA IRAK049F12 (HGX019732) TBX5 R264K acts as a modifier to develop dilated cardiomyopathy in mice independently of T-box pathway.
Human and Animal Cells 454E2(HPS0077) Spatiotemporal imaging documented the maturation of the cardiomyocytes from human induced pluripotent stem cells.
C.elegans tm776 Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration.
Drosophila 5183R-1 , 5183R-2 , 4322R-1 , 4780R-3 , 4780R-1 , 9668R-2 , 31640R-3 , 7000R-2 , 9668R-1 , 7227R-1 , ... An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity.
Algae NIES-48 Highly efficient transgene-free targeted mutagenesis and single-stranded oligodeoxynucleotide-mediated precise knock-in in the industrial microalga Euglena gracilis using Cas9 ribonucleoproteins.
Human and Animal Cells Ba/F3(RCB0805) Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl.
Human and Animal Cells GS-DG1(AES0002) , Mvh-Venus GS(AES0196) Generating Genetically Engineered Mice Using a Spermatogonial Stem Cell-Mediated Method.
C.elegans tm3464 Genetic Suppression of Basement Membrane Defects in Caenorhabditis elegans by Gain of Function in Extracellular Matrix and Cell-Matrix Attachment Genes.
Human and Animal Cells CHO-K1(RCB0285) Biased genome editing using the local accumulation of DSB repair molecules system.
Mice , Human and Animal Cells C57BL/6-Tg(CAG-flpe)36Ito/ItoRbrc(RBRC01834) , TT2(AES0014) Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.
C.elegans tm472 , tm3056 , tm729 The Caenorhabditis elegans Ephrin EFN-4 Functions Non-cell Autonomously with Heparan Sulfate Proteoglycans to Promote Axon Outgrowth and Branching.
Human and Animal Cells 201B7(HPS0063) Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.
Yeast FY29043(JB938) A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast.
C.intestinalis / (O.japonicus) Wild C. int Microinjection of Exogenous Nucleic Acids into Eggs: Ciona Species.
Mice B6.129P2-Gt(ROSA)26Sor(RBRC02657) Novel reporter and deleter mouse strains generated using VCre/VloxP and SCre/SloxP systems, and their system specificity in mice.
Mice B6.Cg-Tg(CAG-Cre)CZ-MO2Osb(RBRC01828) Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
Mice C57BL/6N-Sqstm1/Rbrc(RBRC03941) Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.
DNA material CSII-EF-Venus (RDB05552) CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells.
Human and Animal Cells MRC-5 SV1 TG1(RCB0207) Transgene integration into the human AAVS1 locus enhances myosin II-dependent contractile force by reducing expression of myosin binding subunit 85.