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Species Resource Title
Mice RBRC06803 Targeting EFEMP1 enhances chondrogenesis and inhibits hypertrophic differentiation in a spontaneous osteoarthritis mouse model.
Human and Animal Cells 10T1/2(RCB0247) , ATDC5(RCB0565) Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre-Hypertrophic Chondrocytes.
Mice RBRC02975 Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Human and Animal Cells ATDC5(RCB0565) , 10T1/2(RCB0247) Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2.
Human and Animal Cells ATDC5(RCB0565) Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia.
Human and Animal Cells ATDC5(RCB0565) HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development.
Human and Animal Cells ATDC5(RCB0565) Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
Human and Animal Cells ATDC5(RCB0565) Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model.
Human and Animal Cells RAW 264(RCB0535) Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo.
Human and Animal Cells C2C12(RCB0987) Lactate Promotes Myoblast Differentiation and Myotube Hypertrophy via a Pathway Involving MyoD In Vitro and Enhances Muscle Regeneration In Vivo.
Human and Animal Cells C2C12(RCB0987) Granulocyte-colony stimulating factor enhances load-induced muscle hypertrophy in mice.
Human and Animal Cells C2C12(RCB0987) Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation and myotube hypertrophy.
Human and Animal Cells C2C12(RCB0987) The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy.
Human and Animal Cells ATDC5(RCB0565) A post-translational modification cascade employing HDAC9-PIASy-RNF4 axis regulates chondrocyte hypertrophy by modulating Nkx3.2 protein stability.
Drosophila 3749R-2 A Drosophila model of myeloproliferative neoplasm reveals a feed-forward loop in the JAK pathway mediated by p38 MAPK signalling.
Mice RBRC01828 Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
C.elegans tm311 MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans.
Human and Animal Cells ATDC5(RCB0565) The increase in O-linked N-acetylglucosamine protein modification stimulates chondrogenic differentiation both in vitro and in vivo.
Human and Animal Cells ATDC5(RCB0565) The importance to chondrocyte differentiation of changes in expression of the multiple inositol polyphosphate phosphatase.
Human and Animal Cells ATDC5(RCB0565) Cbfa1 is a positive regulatory factor in chondrocyte maturation.