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  • 検索条件 : 絞込み (MeSH = Intracellular Signaling Peptides and Proteins / metabolism)
生物種 リソース名 タイトル
実験動物マウス RBRC02759 Autophagic degradation of CCN2 (cellular communication network factor 2) causes cardiotoxicity of sunitinib.
メダカ Overexpression of human SAMD9 inhibits protein translation and alters MYC signaling resulting in cell cycle arrest.
ゼブラフィッシュ UAS:GFP Identification of renal stem cells in zebrafish.
実験動物マウス RBRC01834 ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fatty acid desaturation in adipocytes.
ゼブラフィッシュ UAS:GFP Endothelial Notch signalling limits angiogenesis via control of artery formation.
ショウジョウバエ DGRC#119613 Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.
ショウジョウバエ HMS00067 SUMOylation of Warts kinase promotes neural stem cell reactivation.
実験動物マウス RBRC10762 Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice.
遺伝子材料 pCAG-HIVgp (RDB04394) , CS-RfA-CG (RDB04390) , pCMV-VSV-G-RSV-Rev (RDB04393) Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.
実験動物マウス RBRC01765 Loss of Tob1 promotes muscle regeneration through muscle stem cell expansion.
遺伝子材料 pCAGGS (RDB08938) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues.
ショウジョウバエ DGRC#119186 , DGRC#119187 Expression of Human Mutant Preproinsulins Induced Unfolded Protein Response, Gadd45 Expression, JAK-STAT Activation, and Growth Inhibition in Drosophila.
酵母 FY9899 Rcn1, the fission yeast homolog of human DSCR1, regulates arsenite tolerance independently from calcineurin.
ヒト・動物細胞 DT40(RCB1464) , Syk^(-) DT40(RCB1470) Targeting lipid-protein interaction to treat Syk-mediated acute myeloid leukemia.
ショウジョウバエ DGRC#115288 The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism.
ショウジョウバエ DGRC#114504 An EMC-Hpo-Yki axis maintains intestinal homeostasis under physiological and pathological conditions.
酵母 FY21033 The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly.
線虫 tm3858 Genetic analysis of Caenorhabditis elegans Haspin-like genes shows that hasp-1 plays multiple roles in the germline.
線虫 tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
線虫 tm1425 , tm1011 , tm2182 , tm1200 , tm872 , tm1890 , tm331 , tm420 Somatic aging pathways regulate reproductive plasticity in Caenorhabditis elegans.