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  • Search Condition : Filter (MeSH = Intracellular Signaling Peptides and Proteins / metabolism)
Species Resource Title
Mice RBRC10762 Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice.
DNA material pCAG-HIVgp (RDB04394) , CS-RfA-CG (RDB04390) , pCMV-VSV-G-RSV-Rev (RDB04393) Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.
Mice RBRC01765 Loss of Tob1 promotes muscle regeneration through muscle stem cell expansion.
DNA material pCAGGS (RDB08938) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues.
Drosophila DGRC#119186 , DGRC#119187 Expression of Human Mutant Preproinsulins Induced Unfolded Protein Response, Gadd45 Expression, JAK-STAT Activation, and Growth Inhibition in Drosophila.
Human and Animal Cells DT40(RCB1464) , Syk^(-) DT40(RCB1470) Targeting lipid-protein interaction to treat Syk-mediated acute myeloid leukemia.
Drosophila DGRC#115288 The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism.
Yeast FY21033 The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly.
C.elegans tm3858 Genetic analysis of Caenorhabditis elegans Haspin-like genes shows that hasp-1 plays multiple roles in the germline.
C.elegans tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
C.elegans tm1425 , tm1011 , tm2182 , tm1200 , tm872 , tm1890 , tm331 , tm420 Somatic aging pathways regulate reproductive plasticity in Caenorhabditis elegans.
Human and Animal Cells 293T(RCB2202) , HeLa FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) SH2D4A promotes centrosome maturation to support spindle microtubule formation and mitotic progression.
Human and Animal Cells 293(RCB1637) , CACO-2(RCB0988) , LoVo(RCB1639) Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels.
Drosophila DGRC#115511 Metabolic control of progenitor cell propagation during Drosophila tracheal remodeling.
Drosophila 9293Ra-2  Tctp, a unique Ing5-binding partner, inhibits the chromatin binding of Enok in Drosophila.
C.intestinalis / (O.japonicus) Wild C. int cDNA cloning, localization, and candidate binding partners of acid-extractable vitelline-coat protein Ci-v-Themis-like in the ascidian Ciona intestinalis.
Drosophila DGRC#118733 , DGRC#118734 Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.
Human and Animal Cells RAW 264(RCB0535) Extracellular glucose is crucially involved in the fate decision of LPS-stimulated RAW264.7 murine macrophage cells.
Drosophila DGRC#102735 , DGRC#109998 , DGRC#108774 Hippo signaling suppresses tumor cell metastasis via a Yki-Src42A positive feedback loop.