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Species Resource Title
Drosophila Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia.
General Microbes JCM13333 Stenotrophomonas strain CPCC 101271, an intestinal lifespan-prolonging bacterium for Caenorhabditis elegans that assists in host resistance to "Bacillus nematocida" colonization.
Yeast Tschimganine has different targets for chronological lifespan extension and growth inhibition in fission yeast.
Human and Animal Cells 409B2(HPS0076) A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation.
Yeast FY10704 , FY7876 Magnesium depletion extends fission yeast lifespan via general amino acid control activation.
C.elegans tm678 Short-Term Mild Temperature-Stress-Induced Alterations in the C. elegans Phosphoproteome.
C.elegans tm331 , tm789 Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction.
C.elegans tm1978 In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria.
C.elegans tm1502 , tmC18 , tmC12 Decreased mechanotransduction prevents nuclear collapse in a Caenorhabditis elegans laminopathy.
C.elegans tm3116 ATGL-1 mediates the effect of dietary restriction and the insulin/IGF-1 signaling pathway on longevity in C. elegans.
C.elegans tm3223 The Caenorhabditis elegans cysteine-string protein homologue DNJ-14 is dispensable for neuromuscular junction maintenance across ageing.
C.elegans tm1110 KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants.
C.elegans tm2913 , tm1815 , tm1846 The flight response impairs cytoprotective mechanisms by activating the insulin pathway.
C.elegans tm1753 The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans.
Mice RBRC01828 Role of gut microbiota in sex- and diet-dependent metabolic disorders that lead to early mortality of androgen receptor-deficient male mice.
Drosophila Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations.
Drosophila Drosophila Peptide Hormones Allatostatin A and Diuretic Hormone 31 Exhibiting Complementary Gradient Distribution in Posterior Midgut Antagonistically Regulate Midgut Senescence and Adult Lifespan.
C.elegans tm3036 A novel gene-diet pair modulates C. elegans aging.
C.elegans tm2702 Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis elegans.
C.elegans tm2028 Secreted d-aspartate oxidase functions in C. elegans reproduction and development.