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  • Search Condition : Filter (MeSH = Melanosomes / metabolism*)
Species Resource Title
Human and Animal Cells HMV-II(RCB0777) Melanosome degradation in epidermal keratinocytes related to lysosomal protease cathepsin V.
DNA material pEF-HA-mouse RILP (RDB15389) , pEF-HA-mouse RILP-L1 (RDB15390) , pEF-HA-mouse RILP-L2 (RDB15391). The Rab interacting lysosomal protein (RILP) homology domain functions as a novel effector domain for small GTPase Rab36: Rab36 regulates retrograde melanosome transport in melanocytes.
DNA material pCMV-Mreg delta C/MST-mStr(RDB15184) , pCMV-Mreg delta C/MST-mStr-Rab27A-QL/CA (RDB15185) , pmStr-N1-Mreg (RDB15183). The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targetinG tag.
DNA material pEF-FLAG-mouse VAMP-7 (RDB15173) Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.
DNA material pEF-Myc-Kif1c-tail-365-843 (RDB14632) , pEF-Myc-Kif1c-tail-879-1100 (RDB14633) , pEF-T7-GST-Kif1c-tail-879-1100/M-INK (RDB14634) , pEF-Tyrosinase-FLAG (RDB14635). M-INK, a novel tool for visualizing melanosomes and melanocores.
DNA material pEGFP-C1-SKIP/PLEKHM2 (RDB13232) , pmStr-C1-SKIP/PLEKHM2 (RDB13233) , pmStr-N1-Arl8b (RDB13234) , pmStr-N1-Arl8b (Q75L) (RDB13235) , pmStr-N1-mouse Arl8b (RDB15388). Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP.
Clawed frogs / Newts Mitf contributes to melanosome distribution and melanophore dendricity.