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  • Search Condition : Filter (MeSH = Multiple Myeloma / pathology)
Species Resource
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.
DNA material CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G (RDB04392) , pCAG-HIVgp (RDB04394). PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4.
Human and Animal Cells Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma.
Human and Animal Cells Targeting the pro-survival protein MET with tivantinib (ARQ 197) inhibits growth of multiple myeloma cells.
Human and Animal Cells An anilinoquinazoline derivative inhibits tumor growth through interaction with hCAP-G2, a subunit of condensin II.
Human and Animal Cells Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells.
Human and Animal Cells Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib.
Human and Animal Cells By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.
Human and Animal Cells P3-X63-Ag8.653 (RCB0146) Establishment of gerbil-mouse heterohybridoma secreting immunoglobulin of Mongolian gerbil (Meriones unguiculatus) establishment of gerbil-mouse heterohybridoma.
Human and Animal Cells A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma.
Human and Animal Cells Functional B7.2 and B7-H2 molecules on myeloma cells are associated with a growth advantage.
Human and Animal Cells BALL-1 (RCB0256) Generation of monoclonal antibodies against chromosomal antigens that have a high sequence similarity between human and mouse.
Human and Animal Cells Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor.
Human and Animal Cells Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity.