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  • Search Condition : Filter (MeSH = Multiple Myeloma / pathology)
Species Resource Title
Human and Animal Cells RPMI8226(RCB3010) The MIP-1α autocrine loop contributes to decreased sensitivity to anticancer drugs.
Human and Animal Cells Jurkat , KMM-1(RCB0193) , HL60 , RPMI8226(RCB3010) , DAUDI(RCB1640) Potential small guide RNAs for tRNase ZL from human plasma, peripheral blood mononuclear cells, and cultured cell lines.
DNA material CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G (RDB04392) , pCAG-HIVgp (RDB04394). PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4.
Human and Animal Cells MC3T3-E1(RCB1126) Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma.
Human and Animal Cells ST2(RCB0224) By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.
Human and Animal Cells ST2(RCB0224) , MC3T3-E1(RCB1126) Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib.
Human and Animal Cells PCM6(RCB1460) Bortezomib reduces the tumorigenicity of multiple myeloma via downregulation of upregulated targets in clonogenic side population cells.
Human and Animal Cells HeLa(RCB0007) An anilinoquinazoline derivative inhibits tumor growth through interaction with hCAP-G2, a subunit of condensin II.
Human and Animal Cells HeLa(RCB0007) A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma.
Human and Animal Cells ST2(RCB0224) Cell-cell contact between marrow stromal cells and myeloma cells via VCAM-1 and alpha(4)beta(1)-integrin enhances production of osteoclast-stimulating activity.
Human and Animal Cells A431(RCB0202) Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor.
Human and Animal Cells StromaNKtert(RCB2350) Targeting the pro-survival protein MET with tivantinib (ARQ 197) inhibits growth of multiple myeloma cells.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.
Human and Animal Cells P3-X63-Ag8.653(RCB0146) Establishment of gerbil-mouse heterohybridoma secreting immunoglobulin of Mongolian gerbil (Meriones unguiculatus) establishment of gerbil-mouse heterohybridoma.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.
Human and Animal Cells BALL-1(RCB0256) Generation of monoclonal antibodies against chromosomal antigens that have a high sequence similarity between human and mouse.
Human and Animal Cells Functional B7.2 and B7-H2 molecules on myeloma cells are associated with a growth advantage.