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生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ゼブラフィッシュ
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UAS:BoTxBLCGFP, UAS:GCaMP7a
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86725
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Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.
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Nat Commun |
2021-9-6 |
Pubmed
Full text
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ゼブラフィッシュ
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SAIGFF213A, mnr2b-hs:EGFP-TDP-43z, UAS:opTDP-43z
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83105
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Optogenetic TDP-43 nucleation induces persistent insoluble species and progressive motor dysfunction in vivo.
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Neurobiol Dis |
2020-12-1 |
Pubmed
Full text
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ショウジョウバエ
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DGRC#107715
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81469
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α-Synuclein pathology in Drosophila melanogaster is exacerbated by haploinsufficiency of Rop: connecting STXBP1 encephalopathy with α-synucleinopathies.
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Hum Mol Genet |
2024-7-22 |
Pubmed
Full text
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線虫
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tm1978
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75934
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Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling.
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Proc Natl Acad Sci U S A |
2021-9-7 |
Pubmed
Full text
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線虫
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tm5210
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65377
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Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
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PLoS Genet |
2021-3-1 |
Pubmed
Full text
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線虫
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tm781
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65344
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Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
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EMBO J |
2021-2-1 |
Pubmed
Full text
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ラット
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W-Tg(CAG-GFP)184Ys (StrainID=525)
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64061
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Intravenous infusion of mesenchymal stem cells delays disease progression in the SOD1G93A transgenic amyotrophic lateral sclerosis rat model.
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Brain Res |
2021-4-15 |
Pubmed
Full text
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ショウジョウバエ
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DGRC#108479
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59108
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The depletion of ubiquilin in Drosophila melanogaster disturbs neurochemical regulation to drive activity and behavioral deficits.
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Sci Rep |
2020-3-30 |
Pubmed
Full text
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ショウジョウバエ
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8203R-1
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56660
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Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
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Hum Mol Genet |
2019-9-15 |
Pubmed
Full text
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線虫
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tm6026
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tm5782
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tm776
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tm760
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tm1146
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56249
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Axonal Mitochondria Modulate Neuropeptide Secretion Through the Hypoxic Stress Response in Caenorhabditis elegans.
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Genetics |
2018-9-1 |
Pubmed
Full text
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線虫
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tm6026
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56218
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Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
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Elife |
2018-7-10 |
Pubmed
Full text
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線虫
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tm1116
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tm1489
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56217
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The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2.
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Mol Cell Biol |
2018-8-1 |
Pubmed
Full text
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ショウジョウバエ
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4179R-4
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53843
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Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization.
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Mol Cell |
2018-9-6 |
Pubmed
Full text
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線虫
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tm4919
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51426
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Ageing and hypoxia cause protein aggregation in mitochondria.
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Cell Death Differ |
2017-10-1 |
Pubmed
Full text
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実験動物マウス
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RBRC00388
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47308
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Analysis of the protective effects of the α2/δ subunit of voltage-gated Ca2+ channels in brain injury.
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Brain Res |
2017-1-15 |
Pubmed
Full text
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ヒト・動物細胞
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KUM10(RCB2295)
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44742
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Mesenchymal stem cells ameliorate cerebellar pathology in a mouse model of spinocerebellar ataxia type 1.
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Cerebellum |
2014-6-1 |
Pubmed
Full text
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ショウジョウバエ
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6117R-2
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6117R-2
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30808
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Organophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegeneration.
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PLoS One |
2014-2-18 |
Pubmed
Full text
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ショウジョウバエ
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28877
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Drosophila as a screening tool to study human neurodegenerative diseases.
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J Neurochem |
2013-11-1 |
Pubmed
Full text
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ショウジョウバエ
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8091R-2
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21882
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The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila.
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PLoS One |
2012-2-29 |
Pubmed
Full text
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線虫
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tm2912
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4331
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A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans.
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Hum Mol Genet |
2008-10-1 |
Pubmed
Full text
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