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  • Search Condition : Filter (MeSH = Neurodegenerative Diseases / metabolism)
Species Resource Title
Drosophila DGRC#107715 α-Synuclein pathology in Drosophila melanogaster is exacerbated by haploinsufficiency of Rop: connecting STXBP1 encephalopathy with α-synucleinopathies.
C.elegans tm1978 Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling.
C.elegans tm5210 Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
C.elegans tm781 Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
Rats W-Tg(CAG-GFP)184Ys (StrainID=525) Intravenous infusion of mesenchymal stem cells delays disease progression in the SOD1G93A transgenic amyotrophic lateral sclerosis rat model.
Drosophila DGRC#108479 The depletion of ubiquilin in Drosophila melanogaster disturbs neurochemical regulation to drive activity and behavioral deficits.
Drosophila 8203R-1 Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262.
C.elegans tm6026 , tm5782 , tm776 , tm760 , tm1146 Axonal Mitochondria Modulate Neuropeptide Secretion Through the Hypoxic Stress Response in Caenorhabditis elegans.
C.elegans tm6026 Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans.
C.elegans tm1116 , tm1489 The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2.
Drosophila 4179R-4 Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization.
C.elegans tm4919 Ageing and hypoxia cause protein aggregation in mitochondria.
Mice RBRC00388 Analysis of the protective effects of the α2/δ subunit of voltage-gated Ca2+ channels in brain injury.
Human and Animal Cells KUM10(RCB2295) Mesenchymal stem cells ameliorate cerebellar pathology in a mouse model of spinocerebellar ataxia type 1.
Drosophila 6117R-2 , 6117R-2 Organophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegeneration.
Drosophila Drosophila as a screening tool to study human neurodegenerative diseases.
Drosophila 8091R-2 The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila.
C.elegans tm2912 A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans.