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  • Search Condition : Filter (MeSH = Osteoarthritis / metabolism)
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Human and Animal Cells ATDC5(RCB0565) A loss of primary cilia by a reduction in mTOR signaling correlates with age-related deteriorations in condylar cartilage.
Human and Animal Cells ATDC5(RCB0565) Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis.
Human and Animal Cells ATDC5(RCB0565) Deletion of p21 expression accelerates cartilage tissue repair via chondrocyte proliferation.
Human and Animal Cells 10T1/2(RCB0247) The intra-articular injection of RANKL-binding peptides inhibits cartilage degeneration in a murine model of osteoarthritis.
Human and Animal Cells ATDC5(RCB0565) C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
Human and Animal Cells ATDC5(RCB0565) Xanthan Gum Ameliorates Osteoarthritis and Mitigates Cartilage Degradation via Regulation of the Wnt3a/β-Catenin Signaling Pathway.
Human and Animal Cells 10T1/2(RCB0247) Sox4 is involved in osteoarthritic cartilage deterioration through induction of ADAMTS4 and ADAMTS5.
Human and Animal Cells ATDC5(RCB0565) Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling.
Human and Animal Cells ATDC5(RCB0565) Casticin Attenuates Osteoarthritis-Related Cartilage Degeneration by Inhibiting the ROS-Mediated NF-κB Signaling Pathway in vitro and in vivo.
Human and Animal Cells ATDC5(RCB0565) Histone H3K9 methylation is involved in temporomandibular joint osteoarthritis.
Human and Animal Cells ATDC5(RCB0565) Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone.
Human and Animal Cells ATDC5(RCB0565) Artesunate alleviates interleukin‑1β‑induced inflammatory response and apoptosis by inhibiting the NF‑κB signaling pathway in chondrocyte‑like ATDC5 cells, and delays the progression of osteoarthritis in a mouse model.
Human and Animal Cells ATDC5(RCB0565) Isoliquiritigenin suppresses IL-1β induced apoptosis and inflammation in chondrocyte-like ATDC5 cells by inhibiting NF-κB and exerts chondroprotective effects on a mouse model of anterior cruciate ligament transection.
Human and Animal Cells ATDC5(RCB0565) Halofuginone attenuates articular cartilage degeneration by inhibition of elevated TGF‑β1 signaling in articular cartilage in a rodent osteoarthritis model.
Human and Animal Cells ATDC5(RCB0565) Krüppel-Like Factor 2 Regulates Degradation of Type II Collagen by Suppressing the Expression of Matrix Metalloproteinase (MMP)-13.
Human and Animal Cells ATDC5(RCB0565) Biphasic regulation of chondrocytes by Rela through induction of anti-apoptotic and catabolic target genes.
Human and Animal Cells Hep G2(RCB1886) , ATDC5(RCB0565) Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
Human and Animal Cells ATDC5(RCB0565) Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis.
Human and Animal Cells ATDC5(RCB0565) The novel adipokine progranulin counteracts IL-1 and TLR4-driven inflammatory response in human and murine chondrocytes via TNFR1.
Human and Animal Cells ATDC5(RCB0565) 6-Shogaol inhibits chondrocytes' innate immune responses and cathepsin-K activity.