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  • Search Condition : Filter (MeSH = Parkinson Disease / genetics)
Species Resource Title
Human and Animal Cells 201B7(HPS0063) Cell-specific overexpression of COMT in dopaminergic neurons of Parkinson's disease.
Drosophila DGRC#140691 PINK1 Phosphorylates MIC60/Mitofilin to Control Structural Plasticity of Mitochondrial Crista Junctions.
Drosophila DGRC#112001 Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut.
Drosophila Vps35 in cooperation with LRRK2 regulates synaptic vesicle endocytosis through the endosomal pathway in Drosophila.
Drosophila ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson's Disease.
DNA material phRIT2 (RDB16941) , CSII-CMV-MCS-IRES2-Venus (RDB04383) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
C.elegans tm1779 , tm1898 , tm598 Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease.
Human and Animal Cells , Drosophila HeLa , 293T(RCB2202) Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.
C.elegans tm1779 Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases.
C.elegans tm1898 , tm1779 C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease.
C.elegans tm918 , tm1346 Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans.
C.elegans tm918 , tm1346 Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease.
Human and Animal Cells JFP-J1(RCB2309) Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults.
Zebrafish Tg(HuC:Kaede)/rw0130a Quantitative proteomics reveals diverse roles of miR-148a from gastric cancer progression to neurological development.
C.elegans tm1898 Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity.
Drosophila DGRC#109842 , DGRC#109843 The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.
Silkworms o751 Identification of key uric acid synthesis pathway in a unique mutant silkworm Bombyx mori model of Parkinson's disease.
Drosophila 3152R-1 TRAP1 rescues PINK1 loss-of-function phenotypes.
C.elegans tm918 , tm1346 Human DJ-1 and its homologs are novel glyoxalases.
Drosophila The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.