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  • Search Condition : Filter (MeSH = Protein Binding / drug effects)
Species Resource
Human and Animal Cells KGN(RCB1154), 293T(RCB2202) Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants.
Zebrafish Tg(UAS:nfsB-mCherry) Triptolide preserves glomerular barrier function via the inhibition of p53-mediated increase of GADD45B.
DNA material pcDNA5/FRT/TO-SBP-eIF4A1 WT (RDB17295) , pHISMBP-eIF4A1-NTD (WT) (RDB17304) Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor.
Human and Animal Cells Hepa-T1(RCB1156) Unique nuclear localization of Nile tilapia (Oreochromis niloticus) Neu4 sialidase is regulated by nuclear transport receptor importin α/β.
Human and Animal Cells 201B7(HPS0063) , HPS0251 , HPS0252 A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.
C.elegans tm1524 , tm1145 , tm1268 , tm423 LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining.
Arabidopsis / Cultured plant cells, genes sja05800 SENSITIVE TO PROTON RHIZOTOXICITY1, CALMODULIN BINDING TRANSCRIPTION ACTIVATOR2, and other transcription factors are involved in ALUMINUM-ACTIVATED MALATE TRANSPORTER1 expression.
DNA material pQE-Lrp (RDB15924) , MG1655 delta lrp (RDB15921) , MG1655 delta lacZ (RDB15922) , MG1655 delta lacZ delta lrp (RDB15923). Expression of the alaE gene is positively regulated by the global regulator Lrp in response to intracellular accumulation of l-alanine in Escherichia coli.
Human and Animal Cells ATDC5(RCB0565) Nkx3.2 induces oxygen concentration-independent and lysosome-dependent degradation of HIF-1α to modulate hypoxic responses in chondrocytes.
Human and Animal Cells PK-1(RCB1972) Pan-HER-An antibody mixture targeting EGFR, HER2 and HER3 abrogates preformed and ligand-induced EGFR homo- and heterodimers.
Arabidopsis / Cultured plant cells, genes pda13118 In vitro and in vivo evidence for the inhibition of brassinosteroid synthesis by propiconazole through interference with side chain hydroxylation.
Arabidopsis / Cultured plant cells, genes pst15755 Activation of Mitochondrial Protein Phosphatase SLP2 by MIA40 Regulates Seed Germination.
DNA material pCIneoFLAG-LATS1 (RDB14396) , pCIneoFHF-PP1A (RDB14397) , pCIneoFHF-PP2A (RDB14398) , pCIneoLuc-TAZ (RDB14399) , pCIneoFH-TAZ (RDB14400) , pCIneoEGFPC2 (RDB14401) , pLL3.7-FLAG-YAP1 (RDB14395) Validation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motif.
C.elegans tm3229 A stress-responsive system for mitochondrial protein degradation.
C.elegans tm2182 , tm1817 , tm331 The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans.
Human and Animal Cells Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation.
Human and Animal Cells Expression of recombinant alpha and beta tubulins from the yew Taxus cuspidata and analysis of the microtubule assembly in the presence of taxol.
Human and Animal Cells A novel pair of split venus fragments to detect protein-protein interactions by in vitro and in vivo bimolecular fluorescence complementation assays.
Human and Animal Cells PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine.
Human and Animal Cells Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.