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  • Search Condition : Filter (MeSH = Protein Tyrosine Phosphatases / physiology*)
Species Resource Title
Human and Animal Cells DT40(RCB1464) , SHP2^(-) DT40(RCB1502) Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck).
Human and Animal Cells SHP1^(-) DT40(RCB1466) , SHP1^(-)/SHP2^(-) DT40(RCB1501) , SHP2^(-) DT40(RCB1502) , SHIP^(-) DT40(RCB1465) Src homology 2 domain-containing protein-tyrosine phosphatases, SHP-1 and SHP-2, are required for platelet endothelial cell adhesion molecule-1/CD31-mediated inhibitory signaling.
Human and Animal Cells Hep G2(RCB0459) Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells.
DNA material AxCANCre (RDB01748) AxCALacZ Adex1CAlacZ (RDB02726) Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons.
C.elegans tm1191 Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition.
C.elegans tm1191 EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans.
C.elegans tm759 The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6.
Yeast BY23850(BY4742) , BY5209(SH5209 , FY833) , BY5210(SH5210 , FY834) Protein phosphatase Siw14 controls intracellular localization of Gln3 in cooperation with Npr1 kinase in Saccharomyces cerevisiae.
C.elegans tm334 Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans.