• 28 Hits
  • 検索条件 : 絞込み (MeSH = Proteolysis / drug effects)
生物種 リソース名 タイトル
ヒト・動物細胞 C2C12(RCB0987) Protective Effects of the Phytocannabinoid Cannabidiol on Disuse-Induced Muscle Atrophy through Modulation of Proteolysis and Mitochondrial Regulation.
線虫 tm544 Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration.
ヒト・動物細胞 B16F1(RCB2649) Placental Extract Inhibits Melanogenesis by Inducing the Proteasome-Dependent Degradation of Tyrosinase and TRP-1.
ヒト・動物細胞 Huh7(RCB1366) , Huh6(RCB1367) Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs.
藻類 NIES-3377 Development of a rapamycin-inducible protein-knockdown system in the unicellular red alga Cyanidioschyzon merolae.
遺伝子材料 CS-RfA-EG (RDB04391) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells.
遺伝子材料 pCAGGS (RDB08938) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues.
ヒト・動物細胞 A431(RCB0202) A protocol for analyzing the protein terminome of human cancer cell line culture supernatants.
遺伝子材料 pCRISPR_b4galnt1 (RDB13763) CRISPR/Cas9-Mediated Genomic Deletion of the Beta-1, 4 N-acetylgalactosaminyltransferase 1 Gene in Murine P19 Embryonal Carcinoma Cells Results in Low Sensitivity to Botulinum Neurotoxin Type C.
ヒト・動物細胞 HCT116(RCB2979) Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.
ヒト・動物細胞 PC-9(RCB4455) Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
ヒト・動物細胞 HeLa , 293(RCB1637) Mitochondrial ubiquitin ligase activator of NF-κB regulates NF-κB signaling in cells subjected to ER stress.
ヒト・動物細胞 Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.
線虫 Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation.
ヒト・動物細胞 HSC-2(RCB1945) , HSC-3(RCB1975) , SAS(RCB1974) , Ca9-22(RCB1976) Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.
遺伝子材料 p3xFLAG-C/EBP beta (WT) (RDB15962) , p3xFLAG-C/EBP beta (K133R) (RDB15963) Theobromine suppresses adipogenesis through enhancement of CCAAT-enhancer-binding protein β degradation by adenosine receptor A1.
原核生物(大腸菌) Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide.
ヒト・動物細胞 MG6(RCB2403) Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.
ヒト・動物細胞 MDA-MB-453(RCB1192) , MCF7(RCB1904) Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists.
ヒト・動物細胞 TE-1(RCB1894) Targeted inhibition of the COP9 signalosome for treatment of cancer.